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The Silver Locus Product (Silv/gp100/Pmel17) as a New Tool for the Analysis of Melanosome Transfer in Human Melanocyte–Keratinocyte Co-Culture

research The Silver Locus Product (Silv/gp100/Pmel17) as a New Tool for the Analysis of Melanosome Transfer in Human Melanocyte–Keratinocyte Co-Culture

68 citations, March 2008 in “Experimental dermatology”

The new assay can track and measure melanosome transfer between skin cells, confirming filopodia's role in this process.

research The Peripheral Clock Regulates Human Pigmentation

81 citations, October 2014 in “The journal of investigative dermatology/Journal of investigative dermatology”

Certain genes control the color of human hair by affecting pigment production.

research Pharmacological BACE1 and BACE2 Inhibition Induces Hair Depigmentation by Inhibiting PMEL17 Processing in Mice

58 citations, February 2016 in “Scientific reports”

Blocking BACE1 and BACE2 enzymes causes hair color loss in mice.

research Melanocytes: The New Black

93 citations, October 2006 in “The International Journal of Biochemistry & Cell Biology”

Melanocytes are crucial for skin pigmentation and can affect conditions like melanoma, vitiligo, and albinism, as well as hair color and hearing.

research MTORC1 Activity Negatively Regulates Human Hair Follicle Growth and Pigmentation

12 citations, May 2023 in “EMBO reports”

High mTORC1 activity slows hair growth and causes it to lose color.

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Community Join

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community Did Justin Bieber get a Hair Transplant?

in Progress Pictures 296 upvotes 2 years ago

Justin Bieber's hair loss and the various treatments being discussed as potential solutions, including finasteride and hair transplants.

community NW4 -> NW 2.5 (1yr progress) RU 8.5-9% ED and topical Dut .1% + RU 5% 1.5x a week. (+ caffeine redensyl scalp treatment ED)

in Progress Pictures 38 upvotes 11 months ago

The conversation discusses hair regrowth progress from Norwood scale 4 to 2.5 over a year using daily 8.5-9% RU58841, topical Dutasteride 0.1%, RU58841 5% 1.5 times a week, and daily caffeine redensyl scalp treatment.

community maybe some of you need to hear this

in Chat 326 upvotes 2 years ago

Coping with hair loss, the effects of finasteride and minoxidil, and strategies for maintaining self-esteem while experiencing hair loss.

community Advice needed on ‘The Ordinary - Multipeptide serum’. It contains Redensyl, Procapil, Capaxyl, Baicapil and Anagain. All the ingredients individually have shown results but I wanna know if anyone has tried something similar and had side effects? Link of product attached.

in Treatment 8 upvotes 1 year ago

User asks about "The Ordinary - Multipeptide serum" for hair loss, containing Redensyl, Procapil, Capaxyl, Baicapil, and Anagain. Reply states it improves hair appearance but doesn't regrow hair.

community Certified old, at 51, balding since 25, the resurrection!

in Progress Pictures 439 upvotes 3 weeks ago

A 51-year-old shared progress on hair regrowth using topical Minoxidil and Finasteride over four months, noting significant improvement and plans for future hair transplants. The user emphasized the benefits of modern treatments and societal changes in attitudes towards hair loss.

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