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research Sequence And Structure Based Assessment Of Non-Synonymous SNPs In Hypertrichosis Universalis

3 citations, April 2012 in “Bioinformation”

The study investigated the role of non-synonymous SNPs in the TRPS1 gene, which is linked to congenital hypertrichosis, a condition of excessive hair growth. Using SIFT and PolyPhen servers, SNPs rs181507248 and rs146506752 were identified as damaging. Structural analysis revealed that these SNPs significantly altered the secondary and tertiary structures and physiochemical properties of the TRPS1 protein, affecting its interactions and leading to the condition. The refined structure of TRPS1 was submitted to the Protein Model Database with ID PM0077843.

research The Estrogen Receptor 2 (ESR2) Gene in Female-Pattern Hair Loss: Replication of Association with rs10137185 in German Patients

4 citations, April 2014 in “British Journal of Dermatology”

ESR2 gene linked to female-pattern hair loss.

research Scratching the Surface of Skin Development

788 citations, February 2007 in “Nature”

The document concludes that skin stem cells are important for hair growth and wound healing, and could be used in regenerative medicine.

research Molecular Dissection of Mesenchymal–Epithelial Interactions in the Hair Follicle

417 citations, September 2005 in “PLoS biology”

Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.

Large-Scale Genome-Wide Meta-Analysis of Polycystic Ovary Syndrome Suggests Shared Genetic Architecture for Different Diagnosis Criteria

research Large-Scale Genome-Wide Meta-Analysis of Polycystic Ovary Syndrome Suggests Shared Genetic Architecture for Different Diagnosis Criteria

308 citations, December 2018 in “PLOS Genetics”

The research found that PCOS has common genetic factors regardless of how it is diagnosed and is linked to metabolic and reproductive issues.

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community Only Finasteride 1mg once daily for 3 years. Next chapter starts now.

in Progress Pictures 75 upvotes 3 months ago

A user shared their 3-year experience using finasteride for hair loss, reporting significant improvement and no side effects. They are now starting dutasteride and plan to update on progress in a year.

community Began An Intensive Protocol but it's now all habit.

in Hair Systems 2 upvotes 2 years ago

The user follows an intensive hair loss protocol including dutasteride, biotin, black tea, pumpkin seed oil, peppermint shampoo, rosemary conditioner, mukemame, soy milk, lycopene, garlic, magnesium, chamomile, spicy food, citrus bergamot, zinc, multivitamins, kefir, and Greek yogurt. They plan to alternate between pumpkin seed oil and safflower oil and will share before and after pictures.

community Anyone using CB-03-01? What are you thoughts? How do you get it from powder to solution? What strength should be used?

in Treatment 7 upvotes 4 years ago

The conversation is about someone considering using CB-03-01 for hair loss but has ordered finasteride, which they are hesitant to use. They are seeking advice on how to prepare CB-03-01 from powder form and the appropriate strength to use.

community Doc suggested to start using Fin

in Treatment 182 upvotes 4 months ago

A user is seeking advice on hair loss treatment and has been prescribed finasteride. They currently use minoxidil, rosemary oil, and castor oil, and are considering adding dermarolling. Respondents suggest daily use of minoxidil and finasteride, with some recommending additional treatments like ketoconazole shampoo, dermapen, dutasteride, and vitamins.

community Shedding on finasteride only; looking for motivation

in Finasteride/Dutasteride 15 upvotes 6 months ago

A user started finasteride for hair loss and saw improvement, but is now experiencing shedding and thinning in new areas. They added Nizoral due to dandruff caused by finasteride. Replies suggest that shedding is normal around 6 months and advise to stick with the treatment.

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