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GlossaryHair Miniaturization (Shrunken Hair Follicles)

hair follicles shrink, producing thinner and shorter hair strands

Hair miniaturization is a process where hair follicles shrink over time, producing thinner, shorter, and less pigmented hair strands. This phenomenon is commonly associated with androgenetic alopecia (pattern baldness) and can eventually lead to the follicles becoming dormant and ceasing to produce hair altogether.

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research Differential Diagnosis of Female-Pattern Hair Loss

3 citations, January 2016 in “Skin appendage disorders”

Possible causes of female hair loss include androgenetic alopecia, telogen effluvium, cicatricial alopecia, and alopecia areata incognita; diagnosis and treatment require dermoscopy and histopathology.

research A Role for p75 Neurotrophin Receptor in the Control of Apoptosis-Driven Hair Follicle Regression

96 citations, October 2000 in “The FASEB Journal”

The p75 neurotrophin receptor is important for hair follicle regression by controlling cell death.

research Bone Morphogenetic Proteins and Their Antagonists in Skin and Hair Follicle Biology

176 citations, January 2003 in “Journal of Investigative Dermatology”

Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.

research Identification of Hair Shaft Progenitors That Create a Niche for Hair Pigmentation

44 citations, April 2017 in “Genes & development”

Scientists found cells in hair that are key for growth and color.

research Potential Remedial Effects of Solanum Nigrum Berries on Alopecia: An In Vivo Study

January 2024 in “Journal of Natural Remedies”

Solanum nigrum extract may help regrow hair.

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community Taking Charge of Your Hair: The "Big 3 Stack" Explained for 2023

in Research/Science 129 upvotes 1 year ago

The "Big 3 Stack" for hair loss treatment, which includes Minoxidil for hair density improvement, Ketoconazole shampoo for enhancing hair volume and thickness, and Finasteride for blocking hair loss causing hormones. Microneedling can boost Minoxidil's effects.

community 4.5 month finasteride update! What a difference hair makes! To all the people that say just shave it bro, just no.

in Progress Pictures 1593 upvotes 4 years ago

A user's progress pictures and four month finasteride update showing dramatic hair regrowth, as well as their experiences with other treatments like minoxidil. The conversation also includes advice on diet, testosterone levels, and the importance of avoiding baldness for attraction and confidence.

community I came across this 98 year old man and couldn’t help but notice the amazing hair this guy has. His hairline is better than mine and I’m 80 years younger.

in Chat 704 upvotes 1 year ago

User discusses a 98-year-old man with amazing hair and a better hairline than someone 80 years younger. Conversation includes various treatments like Minoxidil, Finasteride, and genetics as factors for hair quality.

community Finasteride gains continue well into year 5

in Chat 118 upvotes 7 months ago

Finasteride can continue to improve hair loss for up to 10 years, with the best results seen when started early. Combining treatments like minoxidil, dermarolling, or RU58841 may enhance effectiveness.

community If Minoxidil Beards are permanent, why should Finasteride be unable to keep Minoxidil Gains on the scalp?

in Minoxidil 104 upvotes 1 year ago

Whether Finasteride can keep alive the hair gained by Minoxidil after quitting it, and why beard hairs are not as susceptible to miniaturization. It is suggested that scalp hair may be dependent on Minoxidil and that DHT could be countered with Finasteride to some extent, but there is no definitive data proving this.

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