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mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials
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4 / 4 resultslearn Tofacitinib
a JAK inhibitor for alopecia areata and other autoimmune conditions
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learn Osteopontin
signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
Research
5 / 1000+ resultsresearch Joint Study of the Associations of HLA-B and the Transmembrane Short Tandem Repeat Polymorphism of MICA Protein with Alopecia Areata Shows Independent Associations of Both with the Disease
Both HLA-B and MICA are independently linked to alopecia areata.
research Forensic DNA Phenotyping
Forensic DNA Phenotyping accurately predicts physical traits and is used in investigations, but needs more diverse population data for confirmation.
research Improving Human Forensics Through Advances in Genetics, Genomics, and Molecular Biology
DNA profiling in forensics has improved, but predicting physical traits and ancestry from DNA has limitations and requires ethical consideration.
research Multi-Ancestry Tandem Repeat Association Study of Hair Color Using Exome-Wide Sequencing
Tandem repeats significantly influence hair color, especially darker shades, across different ancestries.
research DYS459, DYS391, DYS388, And DYS19 Genetic Loci Have High Allelic Frequency In Patients With Prostate Cancer
Certain genetic markers may increase or decrease prostate cancer risk.
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5 / 1000+ resultscommunity Next month marks 2 years on Dutasteride. When does it start working?
A user has been on dutasteride for nearly 2 years with no improvement in hair loss, expressing frustration. Other users suggest checking for other health conditions, getting bloodwork, and considering stopping TRT or trying finasteride.
community The no BS guide to saving your hair without finasteride (improvement in 90% of patients in the study) with a low side effect profile or improvement in 100% of patients but a higher side effect profile and increased dosage. The future is here?
Hair loss treatments, specifically the use of oral minoxidil in combination with micro-needling. Oral minoxidil has been found to improve hair density in 90% of patients with a low side effect profile, but using 5mg per day can result in higher side effects including hypertrichosis and edema. Other treatments mentioned include finasteride and RU58841.
community Occipitalis Muscle Tension Theory
Scalp tension from the occipitalis muscle is theorized to contribute to hair loss, but most believe DHT and genetics are the main causes. Treatments like finasteride and minoxidil are considered more effective than addressing scalp tension.
community Fin/Min/VitD 3 month progress pics
A user shared their positive 3-month experience using finasteride, minoxidil, and vitamin D to treat hair loss, noting significant regrowth and minimal shedding. They also discussed potential side effects and the low likelihood of experiencing them, while being open to answering further questions.
community Feel like I'm a reasonably good responder
The user "OP" reported significant hair regrowth using oral finasteride, oral and topical minoxidil, ketoconazole shampoo, and derma stamping. OP experienced initial shedding but no other side effects.