May 2024 Shh and Dhh affect skin development and can cause tumors, while Ihh does not.
231 citations
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October 1999 in “Journal of Clinical Investigation” Activating the Sonic hedgehog gene in mice can start the hair growth phase.
July 2023 in “PubMed” Sonic hedgehog helps hair follicle stem cells grow and can effectively regenerate hair follicles.
75 citations
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October 2016 in “Genes & Development” Cells in hair follicles help create fat cells in the skin by releasing a protein called Sonic Hedgehog.
145 citations
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November 2018 in “Nature Communications” The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.