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research Early embryonic exposure of freshwater gastropods to pharmaceutical 5-alpha-reductase inhibitors results in a surprising open-coiled “banana-shaped” shell

13 citations , November 2019 in “Scientific reports”

This study found that inhibiting 5α-reductase in molluscs provokes a specific shell morphology, suggesting gastropods might have unique 5α-reductase substrates absent in vertebrates.

research In Vitro Culturing and Harvesting of Human Plucked Hair Follicles

October 2015 in “Journal of Bioresource Management”

This study suggests that plucked human hairs can be used to culture hair follicle cells in vitro, offering a potential, cost-effective alternative to traditional hair transplantation for treating male baldness.

research Hyperbranched glycerol-based core-amphiphilic branched shell nanotransporters for dermal drug delivery

10 citations , May 2016 in “Polymer”

This study reports that novel core-ABS nanocarriers efficiently loaded with dexamethasone and finasteride show potential for dermal drug delivery, exhibiting non-toxic interactions with human keratinocyte cells and skin penetration.

research ROS Balance Autoregulating Core–Shell CeO2@ZIF-8/Au Nanoplatform for Wound Repair

57 citations , March 2024 in “Nano-Micro Letters”

In this study, researchers created a core-shell nanozyme, CeO2@ZIF-8/Au, which autonomously regulates ROS levels to efficiently eliminate bacteria, reduce inflammation, and promote wound healing by balancing ROS generation and scavenging in response to environmental conditions.

research Inhibition of 5α Reductase Impairs Cognitive Performance, Alters Dendritic Morphology and Increases Tau Phosphorylation in the Hippocampus of Male 3xTg-AD Mice

13 citations , January 2020 in “Neuroscience”

This study found that finasteride impaired object recognition memory and altered hippocampal dendritic structures in male 3xTg-AD mice, suggesting potential sex differences in Alzheimer's disease pathology.

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community Haunting study is making me considering cycling fin/dut

in Research/Science 158 upvotes 1 year ago

Concerns about the long-term effects of dutasteride and finasteride on fertility, with discussions on cycling these medications to mitigate risks. The conversation highlights skepticism about study methodologies and the importance of weighing treatment risks against potential fertility issues.

community Testosterone and hair loss seeming irrelevance

82 upvotes 3 years ago

The conversation is about the role of testosterone in hair loss and the effectiveness of different treatments. The conclusion is that DHT is the main culprit for hair loss, and finasteride has been proven to work long-term in maintaining and regrowing hair. Testosterone may have a minor effect, but it is not the primary cause of hair loss.

community Shall I trust my dermatologist? Kindly guide me

in Treatment 1 upvotes 1 year ago

The user is concerned about hair loss and is unsure whether to trust their dermatologist's prescription of minoxidil, fearing potential hormonal effects. Other users suggest using finasteride to block DHT and recommend a blood test to check for underlying issues, while advising against relying solely on shampoos for hair loss treatment.

community My mum, 68. She has decided enough is enough and wants to get some hair back.

23 upvotes 1 year ago

A 68-year-old woman with iron deficiency and hypertension is considering using 5% minoxidil for hair regrowth and plans to see a dermatologist. Some suggest using wigs and focusing on health, while others recommend checking for hormone imbalances and nutritional deficiencies.

community Is trichosol meant to smell like ginger beer?

4 upvotes 2 years ago

A user is using a trichosol-based minoxidil solution to avoid scalp irritation and is asking if it should smell like ginger beer. They like the scent and want to confirm they have the correct product.

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