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In this study, cultured skin equivalents with ovine hair follicle dermal papillae grafted onto nude mice developed follicle-like structures, suggesting a potential model for studying hair follicle development.

This study found that keratinocytes derived from the germinative epithelium of ovine hair follicles have extensive in vitro growth potential, challenging the idea that these cells are solely transit-amplifying.

In this study, researchers used single-cell RNA sequencing to map the hair follicle microenvironment in fine-wool sheep, identifying specific cell types and gene expressions that influence wool fiber diameter, with dermal papilla cells playing a significant role in hair follicle development.

This study identified a target relationship between miR-148a, miR-10a, and BMP7, suggesting these microRNAs influence dermal papilla cell proliferation and may regulate hair follicle growth.

This study found that overexpression of the CUX1 protein promotes proliferation of Hu sheep dermal papilla cells and affects key genes in the Wnt/β-catenin signaling pathway.