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Research

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research Exogen, Shedding Phase of the Hair Growth Cycle: Characterization of a Mouse Model

107 citations , September 2002 in “Journal of Investigative Dermatology”

This study identified a distinct "exogen" phase in the hair cycle during which hair shedding occurs, primarily coupled with the anagen phase, rather than as part of the telogen phase.

research Whether the transient hair shedding phase exist after minoxidil treatment and does it predict treatment efficacy? A retrospective study in androgenetic alopecia patients

March 2025 in “Journal of Dermatological Treatment”

This study explored whether using topical minoxidil can temporarily increase hair shedding, but results are not reported.

research EEMCO Guidance for the Assessment of Hair Shedding and Alopecia

51 citations , January 2004 in “Skin Pharmacology and Physiology”

This review discusses various techniques for evaluating hair shedding and alopecia but reports no new clinical results. The authors emphasize the value of specific clinical and instrumental methods in assessing hair growth.

research Teloptosis, a Turning Point in Hair Shedding Biorhythms

56 citations , January 2001 in “Dermatology”

This study introduces the concept of teloptosis, which influences hair shedding during the telogen phase and affects hair density, highlighting that early or delayed teloptosis has noticeable effects.

research Shedding light on cashmere goat hair follicle biology: from morphology analyses to transcriptomic landascape

8 citations , July 2020 in “BMC genomics”

In this study, ceruloplasmin and keratin 4 were identified as markers that differentiate between growing and resting phases in cashmere goat hair follicles, with keratin 4 being a potential marker for the onset of a new hair cycle.

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Community Join

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community Toppik Hair Fibers as Temporary Solution During Shedding Recovery Phase

in Basic Questions 125 upvotes 1 year ago

The user experienced hair regrowth with finasteride and minoxidil but faced shedding after stopping the treatment. They resumed the treatment and used Toppik hair fibers to mask hair thinning during the shedding phase.

community Dutasteride shedding phase while in Minoxidil

in Treatment 4 upvotes 2 years ago

The user experienced hair shedding with finasteride and found minoxidil helpful for regrowth but insufficient alone. They are considering dutasteride but are concerned about potential shedding similar to their experience with finasteride.

community This shedding phase is brutal man…

590 upvotes 1 year ago

The user is experiencing a difficult shedding phase after starting a hair loss treatment with oral finasteride, topical minoxidil, and microneedling. Despite the shedding, they remain hopeful for regrowth and plan to continue the treatment, encouraged by others' positive results.

community Shedding phase... It's brutal lol

in Progress Pictures 8 upvotes 5 months ago

The user is using finasteride and topical minoxidil for hair loss after previously trying them separately without success. They are experiencing a shedding phase but are committed to the treatment.

community Is this a shedding phase or am i losing my little gains ?

in General 79 upvotes 1 year ago

The user experienced hair loss since 2021, tried various treatments, and is currently using oral minoxidil and finasteride since December 2024. They are experiencing shedding, which is common when starting or stopping treatments, and are advised to continue the current regimen as it may stabilize over time.

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Learn

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learn Hair Transplant

Is shedding normal after a hair transplant? Shedding of transplanted hairs 1–8 weeks after surgery is expected, and regrowth usually starts at 3–5 months. Shock loss of nearby native hair can also happen, so ask your surgeon if shedding persists.

learn PP405

Can PP405 help bald patches caused by stress? PP405 is an experimental topical gel from Pelage Pharmaceuticals that inhibits the mitochondrial pyruvate carrier; its registered Phase 2 trial (NCT06393452) tested it once daily in 78 adults with pattern hair loss, for safety and tolerability. It is not approved, not for sale, and has not been studied in alopecia areata or stress-related shedding.

learn Stemoxydine

Cosmetic ingredient made by L'Oréal

learn Fluridil

Topical anti-androgen sold as a cosmetic lotion

learn Minoxidil

Vasodilator used on the scalp and, at low doses, as a tablet

learn Botox

Can Botox reduce chronic hair shedding? Whether Botox reduces chronic shedding is unknown: one very small 2022 trial in telogen effluvium had no placebo arm, and the blood-flow theory is unproven. Scalp Botox for hair loss is off-label, and all botulinum toxin products carry an FDA boxed warning.

learn Piroctone Olamine

Can Piroctone Olamine reduce hair shedding caused by scalp irritation? Small studies suggest piroctone olamine shampoo may reduce shedding in people with dandruff. It does not treat pattern hair loss.

learn Vitamin B12

Is Vitamin B12 helpful for both men and women experiencing chronic hair shedding? Vitamin B12 may help with hair shedding only if there is a deficiency.

Clinics

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