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research Diagnosis and management of vascular Ehlers-Danlos syndrome: Experience of the UK national diagnostic service, Sheffield

1 citations , March 2023 in “European Journal of Human Genetics”

This retrospective study observed that patients with vascular EDS on long-term angiotensin II receptor blockers or beta-blockers experienced fewer vascular events compared to those without cardiac medication under similar lifestyle and emergency care advice.

Safety Concerns of Paternal Drug Exposure on Fertility, Pregnancy, and Offspring: An Analysis Based on the FDA Adverse Event Reporting System

research Safety concerns of paternal drug exposure on fertility, pregnancy and offspring: An analysis based on the FDA adverse event reporting system

October 2024 in “Andrology”

This study investigated paternal drug exposure using FDA data and identified significant associations with reproductive health risks, including congenital anomalies linked to immunosuppressive drugs, and emphasized specific risk combinations like biologics and abortion, diazepam and small for date baby, and finasteride and cryptorchidism.

research Trichoblastoma with sebaceous and sweat gland differentiation

12 citations , May 2001 in “British journal of dermatology/British journal of dermatology, Supplement”

A rare benign skin tumor showed unusual features of sebaceous and sweat glands, important for correct diagnosis.

Perturbations in Fatty Acid Metabolism and Collagen Production Infer Pathogenicity of a Novel MBTPS2 Variant in Osteogenesis Imperfecta

research Perturbations in fatty acid metabolism and collagen production infer pathogenicity of a novel MBTPS2 variant in Osteogenesis imperfecta

1 citations , May 2023 in “Frontiers in endocrinology”

The researchers reported that the novel MBTPS2 variant p.Glu172Asp found in a male proband is likely pathogenic, consistent with osteogenesis imperfecta symptoms and molecular signatures, including disrupted fatty acid metabolism and collagen production.

Adrenal Disorders and the Pediatric Brain: Pathophysiological Considerations and Clinical Implications

research Adrenal Disorders and the Paediatric Brain: Pathophysiological Considerations and Clinical Implications

38 citations , January 2014 in “International Journal of Endocrinology”

This review highlights that children with adrenal disorders may experience neurological and psychiatric symptoms, with potential long-term cognitive and behavioral effects from excess glucocorticoids.

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Community Join

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community Severe shedding and thinning around 1 year after hair transplant — can transplanted hair grow back?

6 upvotes 1 month ago

The user experienced severe hair shedding and thinning about a year after a hair transplant, despite using finasteride and minoxidil. They are concerned about whether the transplanted hair can regrow or if it is miniaturizing.

community Severe copper deficiency, and also zinc deficiency. Looking for testimonials.

2 upvotes 9 months ago

A 36-year-old man with androgenetic alopecia suspects copper and zinc deficiencies may be accelerating hair loss and is supplementing copper to address this. He is also monitoring blood sugar levels due to previous prediabetes concerns and plans to test for insulin resistance.

community Severe diffuse thinning after scalp inflammation – should I keep fighting or just accept it?

in Finasteride/Dutasteride 4 upvotes 11 months ago

A 23-year-old experiencing severe diffuse thinning after scalp inflammation is considering finasteride as a last resort after stopping minoxidil and using anti-inflammatory medication. Users suggest that inflammation causes temporary shedding and recommend consulting a dermatologist, with some advocating for finasteride as a reliable treatment option.

community Severe diffuse thinning since 13 years old

in Treatment 6 upvotes 1 year ago

A 15-year-old experiencing severe diffuse thinning plans to use minoxidil, dermarolling, and possibly ketoconazole, with hopes to later incorporate finasteride. Concerns about starting finasteride too young and the need for a dermatologist consultation are discussed.

community Severe Hair loss after stopping Rogaine

in Minoxidil 12 upvotes 1 year ago

A 32-year-old male experienced severe hair loss after stopping Rogaine and is considering restarting it along with topical Finasteride and Ketoconazole shampoo due to concerns about oral Finasteride causing gynecomastia. Users suggest that stopping Minoxidil can lead to significant hair loss and recommend Finasteride for better results.

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Learn

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learn Exosomes

What are exosomes and how do they help regenerate hair in cases of severe hair loss? Exosomes are tiny vesicles that promote hair regeneration by signaling hair follicle cells.

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