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      learn Baricitinib

      JAK inhibitor that reduces inflammation and immune attacks on hair follicles, leading to potential hair regrowth, especially in alopecia areata cases

      learn Cyproterone

      a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

      learn Tofacitinib

      a JAK inhibitor for alopecia areata and other autoimmune conditions

      learn Microneedling

      technique to create small wounds in skin to activate collagen production and hair growth

      learn Neem Oil

      natural substance from Neem tree with medicinal and pesticidal properties

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      community Being Safe on Oral Minoxidil: tl;dr on the literature.

      in Research/Science  49 upvotes 1 month ago
      Oral minoxidil is effective for hair loss but can cause cardiovascular side effects, such as pericardial effusion, especially in those with genetic predispositions. Starting with low doses and monitoring cardiovascular health are advised to reduce risks.

      community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

      in Research/Science  62 upvotes 1 year ago
      Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

      community Homemade topical spironolactone

      in Research/Science  26 upvotes 2 years ago
      The potential effectiveness of homemade topical spironolactone in treating hair loss, with studies suggesting it is more effective than finasteride and even minoxidil when used as monotherapy. The conversation also mentions that other anti-androgens are being developed which may soon hit the market.

      community Severe Hair loss after stopping Rogaine

      in Minoxidil  12 upvotes 5 months ago
      A 32-year-old male experienced severe hair loss after stopping Rogaine and is considering restarting it along with topical Finasteride and Ketoconazole shampoo due to concerns about oral Finasteride causing gynecomastia. Users suggest that stopping Minoxidil can lead to significant hair loss and recommend Finasteride for better results.