186 citations
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February 1980 in “Clinical Endocrinology” This study observed that serum levels of oestradiol, testosterone, and androstenedione increase rapidly with the onset of puberty and continue to rise after menarche, with anovulatory cycles being common in early postmenarchal girls.
4 citations
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September 2024 in “Frontiers in Endocrinology” This study found that serum steroid profiling, particularly 11-deoxycortisol, can effectively differentiate between ACC and ACA, while considering sex differences and functional status for other steroids is important.
1 citations
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November 2023 in “Endocrine Connections” This study developed a validated gas chromatography–tandem mass spectrometry assay to assess sex steroid hormones in cerebrospinal fluid, finding substantial levels of DHEA, androstenedione, and testosterone, with strong correlations to serum levels, providing insight into sex steroid dynamics in the human CNS.
5 citations
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April 2024 in “ACS Chemical Neuroscience” This study developed and validated a highly sensitive method using ultrahigh-performance liquid chromatography with tandem mass spectrometry for accurately analyzing nine neuroactive steroids in human serum, which could enhance understanding of disease pathophysiology and support new biomarker and therapeutic discovery.
November 2025 in “European Journal of Endocrinology” This study found that hair steroid profiling is a feasible, non-invasive alternative to serum analysis in adolescents, with androgen levels correlating more strongly with body size and composition in boys than girls.