research 528 Serotonin modulation improves cutaneous wound healing
Serotonin helps wounds heal faster.
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research The cutaneous serotoninergic/melatoninergic system: securing a place under the sun
This review discusses the cutaneous serotoninergic/melatoninergic system's potential role in skin function and resilience against environmental and internal stresses, but does not report new experimental findings.
research Brain allopregnanolone induces marked scratching behaviour in diet-induced atopic dermatitis mouse model
This study demonstrated that allopregnanolone administration caused significant scratching in atopic dermatitis mice, and ethanol-induced scratching may be linked to increased brain allopregnanolone levels.
research On the Role of Melatonin in Skin Physiology and Pathology
This article discusses the potential role of melatonin in protecting skin against stress and maintaining homeostasis, based on its local synthesis and various protective functions, but presents no new clinical results.
research Hedonic sensitivity to natural rewards is affected by prenatal stress in a sex-dependent manner
This study found that early life stress significantly affects hedonic sensitivity to high-palatable food by altering gonadal hormones in prenatally-stressed male and female rats, with sex-dependent changes in reward-related behaviors and neurochemistry.
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5 / 20 resultscommunity DHT Isn't (Directly) Important
Finasteride's potential side effects, especially sexual dysfunction, are discussed, with emphasis on hormonal balance between testosterone and estradiol. Users share experiences with finasteride, minoxidil, and dutasteride, highlighting the variability in side effects and the influence of mindset and lifestyle.
community After praising finasteride on this sub for a while I realised it gave me Brain Fog. I think its related to inhibiting GABA and interferring with mirtazapine (an antidepressant).
Finasteride caused brain fog and reduced the effectiveness of mirtazapine for the user, leading them to stop finasteride and notice improvements in motivation and focus. The user suggests that finasteride might be incompatible with mirtazapine for some people and recommends mirtazapine for those experiencing mental fog from finasteride.
community Hair loss research is a money grab
Hair loss is linked to DHT, with treatments like finasteride and minoxidil being common but not definitive. Economic interests influence research, and there is potential for new treatments like PP405 and RU58841.
community Finasteride does deplete important nuero-active steroids
Finasteride can reduce neuroactive steroids, causing side effects like depression, anxiety, and sexual dysfunction. Some users experience persistent symptoms after stopping finasteride, while others use alternative treatments like topical solutions.
community There’s nothing better on the horizon [RANT]
There is skepticism about new hair loss treatments, with the belief that current options like minoxidil, finasteride, and hair transplants are the best available. Concerns are raised about the systemic side effects of androgen-related treatments, even those marketed as topical, and doubts about the effectiveness of emerging treatments like clascoterone.
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