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Sericin hydrogels heal skin wounds well, regrowing hair and glands with less scarring.

This study found that a sericin-based hydrogel containing Psidium guajava L. extract significantly improved healing of full-thickness burn wounds in mice, with 89.66% wound closure by day 15 compared to 37.16% in controls, and exhibited beneficial effects on inflammation and oxidative stress markers.

This study reports that a heparin-based sericin hydrogel encapsulating basic fibroblast growth factor significantly accelerated wound healing in mice by enhancing vascularization, re-epithelialization, and collagen deposition.

This study developed a bilayer bionic skin scaffold that mimics the skin's structure to resist microbial invasion and enhance wound healing, with in vivo animal studies showing improved collagen deposition, neovascularization, and hair follicle formation.

In this review, researchers evaluated sericin-based drug delivery systems for antimicrobial, anticancer, and neurodegenerative treatments, highlighting its potential benefits and challenges related to molecular variability and formulation stability, suggesting future focus on optimizing extraction and integration with advanced biomedical technologies.