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ELife Assessment: Touch Receptor End-Organ Innervation and Function Require Sensory Neuron Expression of the Transcription Factor Meis2

research ELife Assessment: Touch Receptor End-Organ Innervation and Function Require Sensory Neuron Expression of the Transcription Factor Meis2

February 2024

Meis2 is essential for touch sensation and proper nerve connection to touch receptors in certain skin areas of mice.

Neuronal Plasticity of the Brain-Skin Connection: Stress-Triggered Up-Regulation of Neuropeptides in Dorsal Root Ganglia and Skin via Nerve Growth Factor-Dependent Pathways

research Neuronal Plasticity of the Brain-Skin Connection: Stress-Triggered Up-Regulation of Neuropeptides in Dorsal Root Ganglia and Skin via Nerve Growth Factor-Dependent Pathways

66 citations , July 2007 in “Journal of Molecular Medicine”

Stress increases certain chemicals in the skin and nerves, which might worsen skin conditions.

research The Structure and Organization of Lanceolate Mechanosensory Complexes at Mouse Hair Follicles

106 citations , February 2014 in “eLife”

Lanceolate complexes in mouse hair follicles are essential for touch and depend on specific cells for maintenance and regeneration.

research The Dynamics of the Skin’s Immune System

306 citations , April 2019 in “International Journal of Molecular Sciences”

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

research Tactile Innervation Densities Across the Whole Body

142 citations , September 2020 in “Journal of neurophysiology”

Young adults have about 230,000 tactile nerve fibers, decreasing 5-8% per decade with age.

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community My dad says this is “a mircule”

in Is this regrowth? 514 upvotes 8 months ago

A 31-year-old user experienced hair regrowth and no side effects after switching from finasteride to dutasteride and using minoxidil foam daily. They reported improved hair retention and shared their treatment routine, including a prescription for dutasteride and the use of minoxidil, while humorously discussing side effects and personal experiences.

community Does anyone else sneeze or have their nose run when they microneedle their scalp?

in Microneedling 23 upvotes 1 year ago

Microneedling the scalp can cause sneezing, runny nose, and watery eyes due to nerve stimulation, histamine release, reflex actions, or sinus relief. Several users experience similar symptoms.

community I tried salt water to stop the DHT itch

in Treatment 60 upvotes 2 years ago

Treating the itch associated with male pattern baldness, which is believed to be caused by DHT. Potential treatments discussed include salt water, finasteride, ketoconazole, and RU58841.

community What I've Learned: A Quality of Life Guide

81 upvotes 8 years ago

The post discusses hair loss treatments, specifically using minoxidil, finasteride, nizoral, and sulfur-including shampoo. The author shares personal experiences and tips for application, frequency, and managing side effects, noting significant regrowth with both minoxidil and finasteride.

community Creatine is the opposite of minoxidil !

in Research/Science 293 upvotes 2 days ago

Creatine may counteract minoxidil's hair growth effects by closing potassium ATP channels, potentially leading to hair loss in predisposed individuals. Despite anecdotal reports, there is no conclusive evidence linking creatine to hair loss.

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