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GlossarySensitization

immune system becomes overly reactive to a substance

Sensitization refers to the process by which the immune system becomes overly reactive to a substance, often leading to allergic reactions. For example, in the context of hair and scalp health, repeated exposure to certain hair dyes or chemicals can cause the immune system to recognize these substances as harmful, resulting in inflammation or allergic dermatitis upon subsequent exposures.

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research An Animal Model of Trichloroethylene-Induced Skin Sensitization in BALB/c Mice

36 citations, June 2015 in “International journal of toxicology”

Trichloroethylene causes skin inflammation in mice by increasing certain immune proteins.

research Analysis of Common Treatment Drugs and Allergen Sensitization in Hair Loss Patients

February 2025 in “Journal of Cosmetic Dermatology”

Patch testing is crucial to reduce allergic reactions in hair loss treatments.

research Acute Dermal and Ocular Irritation Testing of Rice Bran Supercritical CO2 Extract (RB-SCE) and 0.5% RB-SCE Essence Product

2 citations, March 2015 in “Toxicology and Environmental Health Sciences”

Rice bran extract caused moderate skin irritation but no eye irritation, while a diluted essence was not irritating to skin and only slightly to guinea pigs.

research Advances in Topical Therapy of Skin Diseases

January 1979 in “PubMed”

New treatments for skin diseases in 1979 showed promising results with fewer side effects.

research Topical Minoxidil Sensitization in Androgenic Alopecia

14 citations, July 1987 in “Contact Dermatitis”

A small percentage of minoxidil users may develop an allergic skin reaction.

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community New Research- Creatine Increasing Scalp DHT Without Corresponding Serum DHT Increase

in Research/Science 123 upvotes 10 months ago

Creatine may increase scalp DHT without affecting serum DHT, potentially speeding up male pattern baldness (MPB) for those genetically prone. Treatments mentioned include Minoxidil, finasteride, and RU58841.