research 1445 UVA-induced senescence in human skin ex vivo leads to impaired wound healing
UVA exposure slows skin wound healing, but α-klotho can reverse this effect.
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5 / 1000+ resultsresearch Stress-induced premature senescence of dermal papilla cells compromises hair follicle epithelial-mesenchymal interaction
This study suggests that stress-induced premature senescence of dermal papilla cells may contribute to hair follicle aging by impairing critical epithelial-mesenchymal interactions and promoting inflammatory cytokine production.
research 1380 Ganoderma lucidum extract attenuates Corticotropin-Releasing Factor (CRF)-induced cellular senescence in human hair follicular cells
This study found that recombinant type III collagen may aid skin aging management by promoting fibroblast proliferation and migration, with a modest impact on inflammatory marker IL-6, though it did not significantly affect TNF-a secretion in vitro.
research Cellular senescence in skin‐related research: Targeted signaling pathways and naturally occurring therapeutic agents
This review discusses cellular senescence in human skin, detailing both beneficial and detrimental effects and suggesting the potential for therapies targeting senescence-related skin disorders, but reports no new clinical results.
research Purified Vitexin Compound 1 Inhibits UVA-Induced Cellular Senescence in Human Dermal Fibroblasts by Binding Mitogen-Activated Protein Kinase 1
This study found that the purified compound VB1 from Vitex negundo seeds may reduce UVA-induced skin aging by targeting MAPK1 and demonstrated its potential in mice.
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