research Recent European legal developments on second medical uses and dosage regimes
This editorial reviews recent European legal developments related to patents on second medical uses and dosage regimes, with no new research findings reported.
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research UK High Court Revokes Escitalopram UK Patent; Validity of Second Medical use Claims Based on Dosage Regimes in the UK; Stay of Proceedings in the UK Courts Pending EPO Opposition Proceedings
The UK High Court revoked Lundbeck's patent for Escitalopram, and second medical use claims based on dosage were not considered novel.
research Court of Appeal can overrule itself to follow the EPO: UK adopts EPO stance on second medical use claims
This ruling by the UK Court of Appeal allows patents for pharmaceuticals based on new dosing regimens and can override previous decisions to align with European Patent Office practices.
research Generic competition and pharma patent strategies - a sequel
The article concludes that recent legal rulings have strengthened the protection of pharmaceutical patents against generic competition.
research Non-invasive assessment of hair regeneration in androgenetic alopecia mice in vivo using two-photon and second harmonic generation imaging
This study used non-invasive imaging techniques to assess hair follicle characteristics in AGA mice, revealing delayed hair shaft alternation and growth stages, as well as testosterone-induced follicle miniaturization, offering potential methods for evaluating AGA on human scalps in vivo.
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5 / 1000+ resultscommunity Second shed sucks (me again xd)
The user is experiencing a second hair shedding phase after 7 months on finasteride, oral minoxidil, and ketoconazole, and is concerned about the sustainability of the treatment. Others encourage continuing the treatment, explaining that shedding is normal and should stabilize over time.
community Second shedding after 14 months of topical minoxidil – has anyone experienced this?
A user experienced a second significant shedding phase 13-14 months after starting 5% topical minoxidil, causing anxiety despite seeing new hair growth. Others shared similar experiences, suggesting that shedding can occur multiple times and recommending patience and possibly adding finasteride or dutasteride.
community Second update: almost 3.5 months min microneedling 1.5mm once a week ketoconazole shampoo 4 times a week
A user's hair loss treatment regimen, which includes minoxidil, ketoconazole shampoo and microneedling; some participants questioned the results due to previous posts about hair transplants, but others agreed that quick results are possible with certain treatments.
community Second shed after second transplant
The user experienced increased hair shedding and thinner hair after a second hair transplant and adjusting doses of oral minoxidil and finasteride. They noted side effects from finasteride disappeared after resuming the medication.
community Second shed or losing the battle? Finasteride and minoxidil
The user experienced initial regrowth with finasteride and minoxidil but is now facing increased hair thinning, possibly due to a second shedding phase. They are considering increasing finasteride dosage or adding dutasteride, despite availability issues, and have started microneedling.
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7 / 801 results- Alfatradiol: Is it safe to use if I’m already on finasteride or minoxidil? No published study has tested alfatradiol together with finasteride or minoxidil, so there is no direct evidence either way — no reported interaction, but also nothing that looked for one. Community members commonly combine them without reporting problems; ask a prescriber before adding a second agent aimed at the same DHT pathway.
- Can I get a second hair transplant if needed? Yes, a second hair transplant is possible if donor hair is available.
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signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
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