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research Effect of dietary polyunsaturated fatty acids and related nutrients on sebum lipids, and skin and hair coat condition in canines

1 citations , February 2005 in “OakTrust (Texas A&M University Libraries)”

In this study, dogs fed Diet B with specific levels of dietary zinc and linoleic acid showed improved skin and hair coat conditions, evidenced by increased hair follicle growth and higher skin lipid scores.

research Ceramide synthase 4 deficiency in mice causes lipid alterations in sebum and results in alopecia

67 citations , April 2014 in “Biochemical Journal”

This study found that mice deficient in ceramide synthase 4 showed altered sebum composition and progressive hair loss due to obstructed hair canals.

research RETRACTED: Serum lipids may causally affect the occurrence of alopecia areata: A Mendelian randomization study

3 citations , June 2024 in “Skin Research and Technology”

Higher LDL lipids may increase alopecia areata risk, while higher triglycerides may decrease it.

research Serum lipidomic changes and sex differences in androgenetic alopecia

February 2024 in “Heliyon”

In this study, AGA patients exhibited distinct lipidomic profiles and higher metabolic syndrome prevalence compared to controls, with certain lipids correlated to key AGA-related factors like DHT, PGD2, and TGF-β1.

research Serum lipid profile and insulin resistance in women with polycystic ovary syndrome (PCOS)

5 citations , June 2018 in “Journal of Diabetes, Metabolic Disorders & Control”

This study found that women with polycystic ovary syndrome have higher triglyceride and fasting glucose levels in obese individuals and higher total cholesterol levels in non-obese individuals compared to healthy women.

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Community Join

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community Hair Loss & Lipids: Why you have sebderm, folliculitis, LPP, inflammation, etc...

131 upvotes 1 year ago

Excess sebum rich in cholesterol and triglycerides can lead to hair loss through inflammation, with treatments like Ciclopirox shampoo, Benzoyl Peroxide shampoo, and Clindamycin gel recommended for managing conditions like seborrheic dermatitis and folliculitis. Pioglitazone is suggested for Lichen Planopilaris, while Omega-3s and reducing processed foods may improve sebum quality, though genetic factors play a significant role.

community Lipisomal Solution (Dutasteride / Tretinoin & Minoxidil & Tretinoin) Horror Story Warning

in Update 12 upvotes 1 year ago

Using liposomal solutions with dutasteride, minoxidil, and tretinoin worsened hair loss due to buildup and scalp issues. Consulting a professional and returning to simpler treatments like finasteride and minoxidil improved the situation.

community My derm said they came up with a new serum that is better then fin? What’s y’all’s thoughts

7 months ago

A new serum claims to enhance hair regrowth by amplifying oxygen delivery, improving the effectiveness of treatments like exosomes and peptides. Users are skeptical, questioning its efficacy compared to established treatments like Minoxidil and Finasteride.

community DHT Harms Scalp Microbiome: DHT Itch is REAL

413 upvotes 1 year ago

Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

community DHT Itch and Oily Scalp Explained (and how to fix it)

90 upvotes 3 months ago

Malassezia overgrowth can worsen oily scalp and inflammation, contributing to hair loss. Treatments include antifungal shampoos, C6/C8 MCT oil, low-dose isotretinoin, finasteride, and dutasteride.

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Learn

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learn Overview

learn sh-Polypeptide-7

learn Baicapil

Could a daily serum with Baicapil help revive dormant hair follicles before it’s too late? Yes, a daily serum with Baicapil may help revive dormant hair follicles.

learn Bimatoprost

Can a lash-growth serum like bimatoprost actually work for your scalp? Bimatoprost (Latisse) is approved for eyelashes, not the scalp; two Allergan phase 2 trials in men with androgenetic alopecia posted results to ClinicalTrials.gov but were never published in a peer-reviewed journal, so scalp use remains off-label and experimental.

learn Hyaluronic Acid

What’s the difference between using hyaluronic acid as a serum on the scalp versus taking it as a supplement? Hyaluronic acid serum hydrates the scalp surface, while supplements may support overall hair health.

learn ceramide

learn Phospholipids

learn Exosomes

Are exosomes applied as a serum, an injection, or combined with other hair treatments? Exosomes are typically injected directly or combined with other hair treatments.

learn Rapamycin

Are there any visible side effects when using rapamycin cream or serum on the scalp? Visible side effects may include skin irritation or redness when using rapamycin on the scalp.

learn Ceramide EOP

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