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This study developed two types of polymeric nanoparticles containing clindamycin phosphate for potential topical acne treatment and found that the NP-AH-CDM-4 formulation preferentially penetrated hair follicles even with sebaceous obstruction, suggesting its promise for more effective acne therapy without causing skin irritation.

This study identified a novel skin site called the follicular epidermis that is prone to cancer, with unique Axin2+ stem cells regulating its homeostasis. The findings suggest current therapeutic approaches may need reconsideration due to new insights into obstruction mechanisms at this site.

In this study, dogs with sebaceous adenitis were treated with oral vitamin A, but responses varied widely, showing improvements in some cases while others experienced no benefit.

This study demonstrates that sebaceous gland loss is a common early feature in primary scarring alopecia and suggests that inflammation of sebaceous glands or ducts may contribute to follicular damage.

This study found that Hoxc13-/- rabbits exhibit complete hair loss on the head and dorsum, providing a potential model for understanding human ECTD-9 and related dermatological conditions.