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research Pre-aggregation of scalp progenitor dermal and epidermal stem cells activates the WNT pathway and promotes hair follicle formation in in vitro and in vivo systems

17 citations , December 2019 in “Stem Cell Research & Therapy”

This study found that their system effectively supports the rapid formation of human hair follicle organoids, providing a platform for studying hair regeneration and drug screening.

research Balding hair follicle dermal papilla cells contain higher levels of androgen receptors than those from non-balding scalp

227 citations , January 1998 in “Journal of Endocrinology”

This study found that dermal papilla cells from balding scalp hair follicles have significantly higher levels of androgen receptors than those from non-balding follicles, supporting their in vivo androgen response.

research Androgen-Dependent Beard Dermal Papilla Cells Secrete Autocrine Growth Factor(s) in Response to Testosterone Unlike Scalp Cells

51 citations , November 1998 in “The journal of investigative dermatology/Journal of investigative dermatology”

In this study, researchers found that while both beard and scalp dermal papilla cells release similar autocrine growth factors, only beard cells increased production and response with testosterone, suggesting these factors enhance androgen-induced hair growth.

research Differences in Expression of Specific Biomarkers Distinguish Human Beard from Scalp Dermal Papilla Cells

41 citations , June 2006 in “Journal of Investigative Dermatology”

This study identified three genes with significantly higher expression in androgen-sensitive beard dermal papilla cells compared to androgen-insensitive scalp cells, suggesting potential novel signaling pathways in hair follicles.

research 496 Evaluation of extracts containing red clover using dermal papilla cells in the development of a scalp treatment system targeting hair loss and hair damage

June 2020 in “Journal of Investigative Dermatology”

This study reported that a treatment serum containing ingredient blends with panthenol, licorice extract, and red clover extract significantly improved hair volume, scalp coverage, and reduced hair breakage over 6 months in individuals with thinning or damaged hair.

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community New Hair Loss Cure: AMP-303 Is Back. It’s what PP405 should have been.

7 upvotes 5 months ago

AMP-303 and AMP-601 are new hair loss treatments targeting dermal papilla cells, with AMP-303 showing early efficacy in transitioning vellus hairs to terminal hairs after one injection. Further clinical trials are planned, and these treatments are seen as promising due to their biologic approach and less frequent application compared to daily treatments.

community Scalp Massages in addition to Fin/Min and Microneedling

in Chat 8 upvotes 2 months ago

Scalp massages are considered a low-risk addition to hair loss treatments like finasteride, minoxidil, and microneedling, potentially offering minor benefits. Most users agree that while massages may improve blood circulation, significant results primarily come from the main treatments.

community NMN Promotes Cell Proliferation and Hair Growth by Reducing Oxidative Stress

14 upvotes 2 years ago

NMN shows promise in promoting hair growth by reducing oxidative stress and weakening androgens. It may be a beneficial addition to hair loss treatments like Minoxidil and Finasteride.

community A new study by Deng and colleagues set out to explore differences between balding and non balding scalps...

39 upvotes 4 years ago

Balding scalps have more androgen receptors, leading to increased TGF-beta, which causes blood vessel loss and hair follicle miniaturization. Blocking androgen signaling and TGF-beta may help prevent hair loss.

community What do you guys think about Stem cell treatments

4 upvotes 5 years ago

Stem cell and exosome injections for hair loss are discussed, with skepticism about their effectiveness and concerns about using non-genetically related stem cells. Dr. Deyarmin's treatments are mentioned, with some users questioning their legitimacy and others expressing curiosity.

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