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GlossarySelective Androgen Receptor Modulators (SARMs)

compounds that selectively target androgen receptors to promote muscle growth

Selective Androgen Receptor Modulators (SARMs) are a class of compounds that bind to androgen receptors in the body, similar to anabolic steroids, but with more targeted effects. They are designed to selectively stimulate muscle and bone growth without significantly affecting other tissues, potentially offering therapeutic benefits for conditions like muscle wasting and osteoporosis with fewer side effects compared to traditional steroids.

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A Phase IIA Randomized, Placebo-Controlled Clinical Trial to Study the Efficacy and Safety of the Selective Androgen Receptor Modulator (SARM), MK-0773 in Female Participants with Sarcopenia

research A Phase IIA Randomized, Placebo-Controlled Clinical Trial to Study the Efficacy and Safety of the Selective Androgen Receptor Modulator (SARM), MK-0773 in Female Participants with Sarcopenia

211 citations, May 2013 in “Journal of Nutrition Health & Aging”

MK-0773 safely increased muscle mass but did not improve muscle strength or function in elderly women with sarcopenia.

research Selective Androgen Receptor Modulators Negatively Regulate Triple-Negative Breast Cancer Growth and Epithelial-Mesenchymal Stem Cell Signaling

56 citations, July 2014 in “PloS one”

SARMs may be an effective treatment for a certain type of breast cancer by blocking cancer growth and spread.

research Chapter 17: Selective Androgen Receptor Modulators (SARMs)

18 citations, January 2001 in “Annual Reports in Medicinal Chemistry”

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

research Abstract P5-09-21: Selective Androgen Receptor Modulators (SARMs): Enobosarm as Targeted Therapy for the Treatment of Androgen Receptor-Positive Breast Cancer

2 citations, December 2013 in “Cancer research”

Enobosarm may effectively treat androgen receptor-positive breast cancer with fewer side effects.

research Nonsteroidal Tissue Selective Androgen Receptor Modulators: A Promising Class of Clinical Candidates

38 citations, October 2005 in “Expert opinion on therapeutic patents”

Selective androgen receptor modulators (SARMs) are a promising type of drug for various health conditions due to their targeted actions.

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Community Join

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community Estrogen is an anabolic for scalp hair, if you mix it with growth stimulants such as oral minoxidil. All we need is an artificial SARM-estrogen that will work only with hair and will be invisible for the rest of the body + some next level AA only for hair – goodbye hair transplant industry

in Transgender 137 upvotes 3 years ago

Hair loss discussion mentions using estrogen mixed with growth stimulants like oral minoxidil for scalp hair growth. Idea proposed for an artificial SARM-estrogen that only affects hair without body side effects.

community Hair gains about 11 months in between pics! Stack is below.

in Progress Pictures 5 upvotes 1 year ago

User experienced hair growth after 11 months using 15% Minoxidil, topical and oral Finasteride, and Ketoconazole Shampoo. Hair remained full even while using steroids and SARMs.

community The hardest hair protocol ever!

in Research/Science 9 upvotes 2 years ago

The user is using RU58841, finasteride, dutasteride, and minoxidil to slow down aggressive hair loss but is still experiencing hair shedding due to high testosterone levels. They plan to use ostarine to lower testosterone and prevent hair loss while maintaining muscle mass, and will continue using the other treatments.

community High DHT with finasteride. Help!

in Finasteride/Dutasteride 6 upvotes 9 months ago

Despite using 5% minoxidil, 0.1% finasteride, and other treatments like microneedling, MK-677, and Cialis, hair loss continues with high testosterone and DHT levels. Considering oral dutasteride but concerned about further increasing testosterone levels.

community Looking for the new RU58841 source in EU

in Treatment 7 upvotes 7 months ago

A user is seeking a new source for RU58841 in the EU after their previous supplier stopped selling it. They mention considering Anagen, Actifolic, Minoxidilmax, and rudirect, and are using a treatment mixing RU58841 with Stemoxydine and Alfatradiol.

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