165 citations
,
October 2013 in “Nature Communications” This study demonstrates that bioengineered salivary gland transplants can fully regenerate gland function, producing saliva and restoring normal swallowing in salivary gland-defective mice, offering potential for xerostomia treatment.
80 citations
,
January 2011 in “Clinical Chemistry and Laboratory Medicine (CCLM)” This study confirmed that the diffusion of cortisol from blood is a biologically endogenous source of hair cortisol, correlating significantly with salivary cortisol levels in healthy humans.
41 citations
,
July 2016 in “Radiation Research” This study found that radiation-induced salivary gland dysfunction in mice involves microvascular damage mediated by ceramide and reactive oxygen species, suggesting ROS scavengers could protect salivary function during radiotherapy for head and neck cancer.
32 citations
,
September 2003 in “European journal of oral sciences” This study found that individuals with ectodermal dysplasias often have a reduced secretion rate of submandibular saliva and altered protein concentrations, suggesting routine salivary tests may be beneficial in this population.
32 citations
,
May 1987 in “The Journal of Clinical Endocrinology & Metabolism” This study found that salivary testosterone concentrations correlated better with hirsutism in women compared to serum testosterone measures, suggesting it may be an effective method for assessing bioavailable testosterone.