63 citations
,
November 2012 in “Journal of Cellular Biochemistry” This paper discusses the role of Runx1 in epithelial biology and pathology, highlighting its dual function as a tumor promoter and suppressor in different contexts, and reports no new experimental findings.
46 citations
,
August 2006 in “Mechanisms of Development” Runx1 is crucial for proper hair structure and development.
34 citations
,
June 2005 in “Developmental dynamics” This study found that Runx3 deficiency in mice affects hair type and shape, suggesting it may regulate hair formation through interactions between dermal and epidermal layers.
24 citations
,
July 2018 in “Stem cells” This study found that Runx1 in hair follicle stem cells modulates lipid metabolism, impacting membrane organization and enhancing signal transduction for cell proliferation in both normal and cancer epithelial cells.
6 citations
,
January 2017 in “Advances in Experimental Medicine and Biology” This review discusses the complex role of Runx family genes in regulating stem cells in blood and skin tissues and reports no new experimental results.