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GlossaryRUNX1

regulates gene expression crucial for blood cell development

RUNX1, also known as Runt-related transcription factor 1, is a gene that plays a crucial role in the regulation of gene expression during the development of blood cells. Mutations in RUNX1 are associated with various blood disorders, including acute myeloid leukemia (AML), making it a significant focus in both clinical and research settings.

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research New Insights into the Role of Runx1 in Epithelial Stem Cell Biology and Pathology

63 citations , November 2012 in “Journal of Cellular Biochemistry”

Runx1 affects hair growth, cancer development, and autoimmune diseases in epithelial tissues.

research Runx3 Is Involved in Hair Shape Determination

34 citations , June 2005 in “Developmental dynamics”

Runx3 helps determine hair shape.

Runx1 Role in Epithelial and Cancer Cell Proliferation Implicates Lipid Metabolism and SCD1 and SOAT1 Activity

research Runx1 Role in Epithelial and Cancer Cell Proliferation Implicates Lipid Metabolism and SCD1 and SOAT1 Activity

24 citations , July 2018 in “Stem cells”

Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.

Runx Family Genes in Tissue Stem Cell Dynamics

research Runx Family Genes in Tissue Stem Cell Dynamics

6 citations , January 2017 in “Advances in Experimental Medicine and Biology”

Runx genes are important for stem cell regulation and their roles in aging and disease need more research.

research Runx1 Transcription Factor Is Involved in the Regulation of KAP5 Gene Expression in Human Hair Follicles

6 citations , January 2006 in “Journal of dermatological science”

Runx1 helps control the KAP5 gene in human hair follicles.

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