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research Superior Root Hair Formation Confers Root Efficiency in Some, But Not All, Rice Genotypes upon P Deficiency

66 citations , December 2016 in “Frontiers in Plant Science”

This study found that rice genotypes exhibit significant variation in root hair properties under low phosphorus conditions, with genotype DJ123 showing particularly efficient root hair growth and phosphorus uptake.

research Faculty Opinions recommendation of Modulation of phospholipid signaling by GLABRA2 in root-hair pattern formation.

June 2003 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

GLABRA2 represses root hair formation by inhibiting a specific gene.

research Faculty Opinions recommendation of Modulation of phospholipid signaling by GLABRA2 in root-hair pattern formation.

September 2003 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

GLABRA2 gene controls root-hair growth by regulating phospholipid signaling.

Knock-Down of Arabidopsis PLC5 Reduces Primary Root Growth and Secondary Root Formation While Overexpression Improves Drought Tolerance and Causes Stunted Root Hair Growth

research Knock-Down of Arabidopsis PLC5 Reduces Primary Root Growth and Secondary Root Formation While Overexpression Improves Drought Tolerance and Causes Stunted Root Hair Growth

38 citations , June 2018 in “Plant & cell physiology/Plant and cell physiology”

This study found that overexpressing PLC5 in Arabidopsis thaliana reduced root growth but improved drought tolerance, and suggests PIP2 is crucial for root hair growth.

research Interaction of OsRopGEF3 Protein With OsRac3 to Regulate Root Hair Elongation and Reactive Oxygen Species Formation in Rice (Oryza sativa)

10 citations , May 2021 in “Frontiers in Plant Science”

This study identified OsRopGEF3 as a key regulator in rice root hair growth, demonstrating that it interacts with proteins to promote reactive oxygen species production, affecting root hair length and width.

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community Low normal DHT but still losing the hairs from the front scalp. Looking for suggestions on what treatment can be used to treat hair loss ?

8 upvotes 2 years ago

A 31-year-old male with low normal-range testosterone and DHT is experiencing significant hair loss from the front scalp. He has tried Minoxidil, vitamin D3 and B12 supplements, and exercises regularly but is still seeking the root cause and effective treatment.

community Phase II topical dut study - outperforms oral fin with a minor DHT reduction

in Research/Science 61 upvotes 7 months ago

Topical dutasteride 0.05% is more effective for hair growth than oral finasteride 1mg, with minimal DHT reduction. The formulation uses castor oil and MCTs for better absorption but is not widely available until 2028.

community Possible natural pp405 solution

in Research/Science 45 upvotes 1 year ago

Rotenone, a natural plant extract, may promote hair growth by increasing LDH activity and blocking MPC in the scalp, but it carries risks due to its toxicity. The suggested formulation includes Barbasco extract, DMSO, propylene glycol or PEG-400, ethanol, and a carrier oil.

community Attempting PP-405 topical gel reformulation

20 upvotes 4 days ago

A user is attempting to reformulate a topical gel using PP-405 for hair loss, aiming to enhance its effectiveness with additional compounds. They discuss the potential of PP-405 compared to other treatments like Minoxidil and GT20029, and emphasize the importance of proper formulation for efficacy.

community DHT Isn’t the Only Factor in Hair Loss and That Might Be the Key to a Real Cure

373 upvotes 6 months ago

Hair loss involves more than just DHT, with genetic factors like TRPS affecting hair follicles. Treatments such as Amplifica's AMP-601 and AMP-303 target stem cells for potential hair growth solutions.

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