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research Bisindolylmaleimide Protein Kinase C Inhibitors Delay the Decline in DNA Synthesis in Mouse Hair Follicle Organ Cultures

11 citations , January 1997 in “Skin Pharmacology and Physiology”

A certain inhibitor can slow down the decrease in DNA creation in mouse hair follicles, which might help with hair growth.

research Interleukin-1β Is Differentially Expressed by Human Dermal Papilla Cells in Response to PKC Activation and Is a Potent Inhibitor of Human Hair Follicle Growth in Organ Culture

38 citations , March 1997 in “Journal of interferon & cytokine research”

IL-1β inhibits human hair follicle growth.

research IL-1 Alpha Inhibits Human Hair Follicle Growth And Hair Fiber Production In Whole-Organ Cultures

30 citations , August 1993 in “PubMed”

IL-1 alpha stops hair follicle growth and hair production.

research Protein Kinase C as a Therapeutic Target

87 citations , September 2006 in “Clinical Cancer Research”

Protein Kinase C shows promise for cancer treatment, but more research is needed to develop effective inhibitors.

research Defining the Short-Term and Long-Term Skin Manifestations of COVID-19: Insights After More Than Three Years of the Pandemic

1 citations , October 2023 in “Romanian Journal of Morphology and Embryology”

COVID-19 can cause various skin issues, but long-term skin problems are rare.

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community Pelage Announces Positive Results of Phase 2a Trials for PP405

in Update 297 upvotes 4 months ago

PP405 shows promise in treating severe hair loss, with 31% of users experiencing over 20% hair density increase in four weeks, faster than minoxidil and finasteride. Some users are skeptical about the results' significance and long-term efficacy.

community 5 Months on Minoxidil and Finasteride

in Is this regrowth? 1791 upvotes 2 months ago

The user experienced significant hair regrowth after 5 months using Minoxidil and Finasteride, specifically Hims chewables. They noted an increase in depression as a side effect.

community I promise it works. Topical minox + finasteride

in Update 1721 upvotes 9 months ago

Topical minoxidil and oral finasteride can effectively improve hair growth and slow hair loss, though results may vary. Consistency is important for achieving significant improvement.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 1 year ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community 3+ years on 1mg Fin, wasn’t too far gone but happy to have my temples back.

in Progress Pictures 521 upvotes 2 years ago

The user "Potvin_Sucks_" shared their positive experience with using finasteride pills for hair loss. They also mentioned making lifestyle changes such as quitting smoking and exercising regularly. Other users discussed the possibility of using topical finasteride and online hair loss prescription delivery services.

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