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research Bisindolylmaleimide Protein-Kinase-C Inhibitors Delay the Decline in DNA Synthesis in Mouse Hair Follicle Organ Cultures

11 citations , January 1997 in “Skin Pharmacology and Physiology”

This study found that bisindolylmaleimide PKC inhibitors increased DNA synthesis in mouse hair follicles, suggesting that PKC may inhibit hair follicle proliferation.

research Defining the short-term and long-term skin manifestations of COVID-19: insights after more than three years of the pandemic

1 citations , October 2023 in “Romanian Journal of Morphology and Embryology”

This review analyzed 109 articles to classify skin lesions associated with COVID-19 and their frequency during the disease, but found no conclusive evidence on long-term persistence of specific types due to rarity.

research Immune-mediated Coombs negative intravascular haemolysis in systemic lupus erythematosus (SLE)

August 2021 in “BMJ Case Reports”

This case report details a 27-year-old woman's diagnosis of systemic lupus erythematosus with immune-mediated intravascular haemolysis, which improved with steroid treatment.

Polygonum Multiflorum Extract Supports Hair Growth by Elongating Anagen Phase and Abrogating the Effect of Androgen in Cultured Human Dermal Papilla Cells

research Polygonum multiflorum extract support hair growth by elongating anagen phase and abrogating the effect of androgen in cultured human dermal papilla cells

15 citations , May 2020 in “BMC complementary medicine and therapies”

This study found that Polygonum multiflorum extract may promote hair growth by increasing anagen duration and activating dermal papilla cells in human hair follicles, as observed in cultured cell models.

research Interleukin-1β Is Differentially Expressed by Human Dermal Papilla Cells in Response to PKC Activation and Is a Potent Inhibitor of Human Hair Follicle Growth in Organ Culture

38 citations , March 1997 in “Journal of interferon & cytokine research”

This study suggests that IL-1β produced by dermal papilla cells, regulated by protein kinase C, may inhibit human hair follicle growth through paracrine signaling.

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community 2 months into minoxidil 6% fin .3% tret .025% topical

in Is this regrowth? 260 upvotes 1 year ago

The user is experiencing solid hair regrowth after two months using a regimen of minoxidil foam, a 3-in-1 topical spray containing finasteride and tretinoin, and weekly dermastamping. They report no side effects and attribute success to the combination of treatments and a supportive diet and lifestyle.

community Pelage Announces Positive Results of Phase 2a Trials for PP405

303 upvotes 1 year ago

PP405 shows promise in treating severe hair loss, with 31% of users experiencing over 20% hair density increase in four weeks, faster than minoxidil and finasteride. Some users are skeptical about the results' significance and long-term efficacy.

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research Bisindolylmaleimide Protein-Kinase-C Inhibitors Delay the Decline in DNA Synthesis in Mouse Hair Follicle Organ Cultures

research Defining the short-term and long-term skin manifestations of COVID-19: insights after more than three years of the pandemic

research Immune-mediated Coombs negative intravascular haemolysis in systemic lupus erythematosus (SLE)

research Polygonum multiflorum extract support hair growth by elongating anagen phase and abrogating the effect of androgen in cultured human dermal papilla cells

research Interleukin-1β Is Differentially Expressed by Human Dermal Papilla Cells in Response to PKC Activation and Is a Potent Inhibitor of Human Hair Follicle Growth in Organ Culture

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community 2 months into minoxidil 6% fin .3% tret .025% topical

community Pelage Announces Positive Results of Phase 2a Trials for PP405

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Dr. Ricardo Flaminio Rojas, MD

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Dr. Robert Haber, MD, FISHRS

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Robin Lennon

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