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research Maintenance of Epidermal Progenitor Function Through the mRNA Degradation and Translation Pathways

April 2018 in “Journal of Investigative Dermatology”

The protein DDX6 helps keep skin cells renewing properly by controlling the production of certain other proteins and breaking down those that cause cells to mature too quickly.

research Dermal Wnt/β-Catenin Activation Tunably Controls Hair Follicle Initiation

May 2018 in “Journal of Investigative Dermatology”

Activating Wnt in skin cells controls the number of hair follicles by directing cell movement and fate.

research A Perspective on RNAi-Based Biopesticides

140 citations, February 2020 in “Frontiers in Plant Science”

RNAi-based biopesticides could be safe and effective for pest control with careful development and risk assessment.

research MicroRNA Control of Signal Transduction

1066 citations, March 2010 in “Nature Reviews Molecular Cell Biology”

MicroRNAs are crucial in controlling cell signaling, affecting cancer and tissue regeneration.

research Montagna Symposium 2015: Harnessing Stem Cells to Reveal Novel Skin Biology and Disease Treatments

April 2016 in “Journal of Investigative Dermatology”

The symposium showed that stem cells are key for understanding and treating skin diseases and for developing new skin models and therapies.

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community Since there is so much hype for cosmeRNA and HMI-115...

in Chat 48 upvotes 1 year ago

Exploring different treatments for hair loss, such as cosmeRNA and HMI-115 which are small interference messenger RNA that inhibits the DHT receptor and an antibody that binds to the prolactin (PRL) receptor respectively; and researching mechanism and environment of hyperresponders.

community Finally about to start Pyriltamide (ONLY Pyriltamide)

in Chat 63 upvotes 3 months ago

A user is excited to start using Pyriltamide for hair loss after experiencing side effects from topical finasteride. Other users discuss the potential and skepticism of Pyriltamide compared to older treatments like finasteride and RU58841.

community How do we only have two treatments to combat hair loss at this point in time?

in Chat 211 upvotes 1 year ago

The post discusses frustration over the limited and not always effective treatments for hair loss, mainly Minoxidil and Finasteride. The conversation includes mentions of potential new treatments like GT20029, HMI-115, CosmeRNA, KX-826, and microneedling, but also highlights the challenges of funding and prioritizing research in this area.

community Kintor stealing pictures from a hair transplant clinic to promote their failed product (KX826, Pyrilutamide)

in Product 315 upvotes 3 months ago

Kintor is accused of using fake pictures to promote their product, Pyrilutamide (KX826), which failed Phase 3 trials. Users express disappointment and note similar false advertising has occurred with finasteride and minoxidil.

community Q1 2024 is done. And kintor is completely silent about GT20029.

in Research/Science 32 upvotes 7 months ago

The conversation discusses the lack of updates on GT20029 for hair loss treatment, with some users noting recent reports indicating ongoing data collection. There are mentions of other treatments like Pyrilutamide and Minoxidil.

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