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research Influence of Massage and Occlusion on the Ex Vivo Skin Penetration of Rigid Liposomes and Invasomes

39 citations, November 2013 in “European journal of pharmaceutics and biopharmaceutics”

Massage increases how deep both rigid and flexible liposomes can go into skin, with flexible ones going deeper, and covering the skin (occlusion) helps rigid ones more.

research Potential of Nanoparticles as Permeation Enhancers and Targeted Delivery Options for Skin: Advantages and Disadvantages

130 citations, August 2020 in “Drug Design Development and Therapy”

Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.

research Invasomes: Vesicles for Enhanced Skin Delivery of Drugs

6 citations, January 2016 in “Springer eBooks”

Invasomes effectively deliver drugs through the skin and have potential for improved treatments.

research The Evolution of Emerging Nanovesicle Technologies for Enhanced Delivery of Molecules into and Across the Skin

1 citations, February 2024 in “Pharmaceutics”

Nanovesicles improve drug delivery through the skin, offering better treatment outcomes and fewer side effects.

research Dutasteride Nanocapsules for Hair Follicle Targeting: Effect of Chitosan-Coating and Physical Stimulus

26 citations, February 2020 in “International Journal of Biological Macromolecules”

Chitosan-coated dutasteride nanocapsules improve hair treatment, and physical stimulation boosts effectiveness.

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community 27M Struggling with 5-Month Treatment Limit on Minoxidil and Finasteride, Seeking AR Blocker Advice

in General 111 upvotes 1 week ago

A 27-year-old male is experiencing a recurring pattern of hair loss after 5 months of using oral minoxidil and finasteride, despite initial success. He is considering using topical androgen receptor blockers like RU58841, pyrilutamide, or clascoterone to address potential androgen receptor hypersensitivity.

community 5+ year users, what has your experience been on fin and dut?

in Chat 30 upvotes 1 month ago

Users discussed their experiences with hair loss treatments, primarily finasteride (Fin) and dutasteride (Dut), often combined with minoxidil (Min) and derma rolling. Many reported mixed results, with some seeing slowed hair loss and others experiencing side effects or minimal improvement.

community About to throw in towel. I just don't know anymore

in Treatment 8 upvotes 2 months ago

The user is experiencing severe side effects from finasteride, including sleep issues, depression, and gynecomastia, and is considering stopping the medication. They are exploring other treatments like RU58841 and dutasteride but are hesitant due to potential side effects.

community Where did this idea come from: dermastamp better than dermaroller?

in Microneedling 10 upvotes 5 months ago

Dermastamps are preferred over dermarollers for microneedling due to precision and reduced risk of scarring. Dermastamps allow for controlled, vertical needle entry, while dermarollers may cause more damage with sideways needle entry.

community Minoxidil actually reduces wrinkles

in Research/Science 209 upvotes 8 months ago

Minoxidil may improve or worsen skin quality, with topical forms causing dryness and wrinkles, possibly due to alcohol content, while oral forms have fewer side effects. Some users consider using tretinoin to mitigate negative effects.

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