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Did you mean Rho-associated kinase inhibitor?

GlossaryROCK inhibitor (Rho-associated kinase inhibitor)

blocks enzymes involved in cell contraction and motility

A ROCK inhibitor, also known as a Rho-associated kinase inhibitor, is a type of drug that blocks the activity of Rho-associated kinases (ROCKs). These enzymes play a crucial role in various cellular functions, including contraction, motility, proliferation, and apoptosis. By inhibiting ROCKs, these drugs can help treat conditions like hypertension, glaucoma, and even promote hair growth in cases of alopecia by improving blood flow and reducing inflammation.

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research Establishment of an Efficient Primary Culture System for Human Hair Follicle Stem Cells Using the Rho-Associated Protein Kinase Inhibitor Y-27632

16 citations, March 2021 in “Frontiers in cell and developmental biology”

A new method using Y-27632 improves the growth and quality of human hair follicle stem cells for tissue engineering and therapy.

research Dysregulated Behavior of Hair Follicle Stem Cells Triggers Alopecia and Provides Potential Therapeutic Targets

3 citations, May 2022 in “Experimental Dermatology”

Misbehaving hair follicle stem cells can cause hair loss and offer new treatment options.

research Efficient Establishment of an Optimized Culture Condition for Cashmere Goat Primary Hair Follicle Stem Cells

January 2023 in “Journal of animal science/Journal of animal science ... and ASAS reference compendium”

Adding Y-27632 and bFGF to the culture medium greatly improves goat hair follicle stem cell growth and quality.

research Targeting the Hippo/YAP/TAZ Signalling Pathway: Novel Opportunities for Therapeutic Interventions into Skin Cancers

7 citations, August 2022 in “Experimental dermatology”

Blocking YAP/TAZ could be a new way to treat skin cancer.

research Boosting and Rescuing Epidermal Superior Population from Fresh Keratinocyte Cultures

15 citations, August 2013 in “Stem Cells and Development”

The method increases stem-like cells for better skin regeneration.

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community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 44 upvotes 4 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.