research Case Report Vitamin A Toxicity and Hypercalcemia
This study found that the most likely cause of hypercalcemia in a patient with symptoms of hypervitaminosis A and a history of chronic vitamin A ingestion was vitamin A toxicity.
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5 / 1000+ resultsresearch DGAT1 Modulates Hair Cycling and Is Essential for Retinoid Homeostasis in the Skin
This study found that the enzyme encoded by Dgat1 acts as a retinol acyltransferase in murine epidermis, protecting against retinoid toxicity and alopecia by preventing retinol accumulation.
research Finasteride Induced Clinical Ocular Toxicity
This study observed retinal and optic nerve damage in patients who had taken finasteride, suggesting potential ocular toxicity associated with the drug's use.
research Retinol Esterification by DGAT1 Is Essential for Retinoid Homeostasis in Murine Skin
This study found that DGAT1 functions as a key enzyme in murine skin to regulate retinoic acid levels and prevent retinoid toxicity, impacting hair cycle and sensitivity to retinol.
research Preliminary toxicity profile of arotinoids SMR-2 and SMR-6 in male B6D2F1 mice*1
This study found that SMR-2 and SMR-6, analogs of retinoic acid and retinol, were approximately 100 times more toxic than retinoic acid in mice, inducing hypervitaminosis A and affecting various organs and tissues.
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5 / 1000+ resultscommunity Where can I find Minoxidil free multi-ingredient topicals?
The conversation is about finding a topical hair loss treatment that includes finasteride or dutasteride but excludes minoxidil, with a preference for additional ingredients like retinol, hydrocortisone, or ketoconazole, and avoiding propylene glycol. The user is already using oral minoxidil and experienced side effects with oral finasteride.
community Before Oral Minoxodil vs 3 months (2.5)
The user is using 2.5mg oral minoxidil and Nizoral shampoo for hair regrowth, noticing some improvement. They are considering increasing the dosage and exploring alternatives to topical minoxidil/finasteride due to concerns about toxicity to cats.
community Tretinoin for some men(not all) can cause non-telogen effluvium hair loss
Tretinoin can cause non-telogen hair loss in some men by inducing catagen-like changes in hair follicles and through retinoid toxicity, especially when used with minoxidil. Some users report hair loss even when using retinoids on the face, while others experience benefits when combined with treatments like finasteride and minoxidil.
community Leaving minoxidil for only 1 hour on scalp - how to maximize effectiveness?
The user is trying to maximize minoxidil's effectiveness by applying it for only one hour to avoid spreading it to furniture and pets, especially cats. They experience side effects when combining minoxidil with dermarolling and are considering alternatives like oral minoxidil or microneedling.
community Is Retinol effective by itself?
Retinol is not effective alone for hair loss; tretinoin is more potent and sometimes mixed with minoxidil. Retinoids do not stop hair loss, and finasteride or dutasteride is necessary for that.
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5 / 800 results- Does retinol improve scalp health or help other hair growth treatments work? No trial has tested over-the-counter retinol for hair; the studies used prescription tretinoin (retinoic acid), mostly in the lab, with mixed results. Retinoids need caution in pregnancy, so ask a doctor first.
- Can retinol help enhance the absorption of ingredients like minoxidil or peptides? No human study has measured whether retinol increases scalp absorption of minoxidil or peptides. Retinoids thicken rather than thin the epidermis, and they can irritate skin and need caution in pregnancy.
- Is retinol safe to use on the scalp, or should it be diluted to avoid irritation? There is little research on retinol on the scalp; retinoids often cause redness, dryness and peeling, and long-term scalp safety has not been studied. Avoid retinoids if pregnant or trying to conceive, and ask a doctor before use.
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