12 citations
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May 2017 in “Journal of pharmaceutical and biomedical analysis” In this study, researchers developed a method using scalp cyanoacrylate biopsy and advanced imaging techniques to effectively measure and visualize the distribution of anti-dandruff shampoo ingredients zinc pyrithione and climbazole within the scalp follicular infundibulum.
43 citations
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October 2002 in “International Journal of Cosmetic Science” This study found that 1% ketoconazole and 1% piroctone olamine shampoos increased hair shaft thickness and reduced hair shedding in men with telogen effluvium and androgenic alopecia associated with dandruff.
89 citations
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January 2013 in “Acta dermato-venereologica” This review examines dandruff and seborrheic dermatitis, highlighting the role of Malassezia yeasts in inflammation and hyper-proliferation, and reports no new clinical findings.
46 citations
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September 2011 in “British journal of dermatology/British journal of dermatology, Supplement” This study found that certain zinc pyrithione shampoos effectively deliver antifungal agents to the scalp's follicular infundibulum, correlating with reduced Malassezia populations, likely influenced by particle size optimizing such delivery.
24 citations
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November 2015 in “International Journal of Cosmetic Science” This study demonstrated that oxidative stress contributes to dandruff, and using a potentiated ZPT shampoo improves scalp and hair condition by reducing oxidative stress.
16 citations
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May 2017 in “Journal of cosmetic dermatology” In this clinical study, the use of potentiated zinc pyrithione shampoo improved scalp health and hair surface characteristics, suggesting that unhealthy scalp conditions may negatively impact pre-emergent hair's cuticle surface.
August 2020 in “Prosiding Farmasi” This study reviewed existing literature and reported that 1% Zinc pyrithione in anti-dandruff shampoo effectively inhibits the growth of fungi responsible for dandruff, aligning with the regulatory limits set by Indonesian health authorities.
40 citations
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January 2018 in “International journal of trichology” This article reviews the relationship between scalp conditions and hair health, suggesting that shampoos with Malassezia inhibitory agents may help reduce premature hair loss, but it presents no new clinical results.
4 citations
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January 2021 in “Skin appendage disorders” In this study, researchers found that washing hair 5–6 times per week results in higher satisfaction and better objective and subjective hair and scalp conditions among Asian populations, with no observed detrimental effects from frequent washing.
4 citations
,
February 2018 in “Jurnal teknologi” This study found that Kaempferia galanga ethanolic extract has potential as an antifungal agent in an oil-in-water cream formulation, exhibiting stable physicochemical properties in laboratory tests.
January 1997 in “Elsevier eBooks” This chapter describes the functions and purposes of hair care cosmetics, including shampoos, hair growth promoters, and grooming products, without reporting new experimental findings.
2 citations
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March 2004 in “Journal of the American Academy of Dermatology” This study found that a 60-second timed hair count is a practical and reproducible method for women to document hair shedding and treatment response at home, with significant differences in hair shedding observed between age groups in follow-up results.
14 citations
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September 2021 in “International journal of molecular sciences” This review details how zinc pyrithione's anti-fungal activity makes it a successful treatment for dandruff and seborrheic dermatitis, by effectively targeting Malassezia yeast in the scalp.
3 citations
,
September 2021 in “BioEssays” This article discusses a novel hypothesis on the role of hair follicles in dandruff pathogenesis, focusing on immune response and inflammation due to scalp microbiota changes and sebum by-products, but reports no new clinical results.
7 citations
,
January 2021 in “Journal of Cosmetics Dermatological Sciences and Applications” This review discusses the characteristics and interactions of the scalp barrier, dandruff, and scalp sensitivity but reports no new clinical results.
1 citations
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March 2004 in “Journal of the American Academy of Dermatology” This study reports a strong association between the MICA locus, specifically the MICA∗3-DR∗6-DQ6 haplotype, and Alopecia Areata in families.
January 2025 in “International Journal of Herbal Medicine” This review highlights that while dandruff affects over 50% of humans and cannot be fully eradicated, it can be controlled through chemical treatments that may cause side effects or herbal remedies such as Neem and Tea tree oil, which have longstanding use in hair care.
1 citations
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March 2021 in “Current Dermatology Reports” This review highlights various alternative and complementary treatments for androgenic alopecia, noting that while only two FDA-approved options exist, increased awareness among dermatologists of supportive evidence for other therapies may better inform patient education.
13 citations
,
March 2024 in “Cell Transplantation” This review highlights the need for improved methods in cosmetic safety assessment, emphasizing the potential of engineered skin tissue for more effective detection and toxicological evaluation of cosmetic products, compared to traditional methods.
4 citations
,
January 2023 in “Frontiers in Medicine” This review discusses the use of zinc supplementation in dermatology for various skin conditions and reports no new clinical results, providing references for its application.
February 2026 in “American Journal of Clinical Dermatology” Spironolactone is effective for treating female hair loss, with new treatments like clascoterone showing promise.
49 citations
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January 1991 in “Food and chemical toxicology” In this study, zinc chloride was found to be severely irritant to the skin in rabbit, guinea-pig, and mouse models, while zinc oxide, zinc sulphate, zinc pyrithione, and zinc undecylenate showed minimal to no irritancy.
February 2013 in “Journal of the American Academy of Dermatology” The zinc pyrithione hair care system improves scalp hydration and reduces water loss.
25 citations
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January 2019 in “Journal of Pharmacy And Bioallied Sciences” This study concluded that the formulated polyherbal shampoo is a chemical-free product with nourishing, conditioning, cleansing, and antimicrobial effects.
25 citations
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September 2005 in “Journal of Investigative Dermatology Symposium Proceedings” Adding zinc to pyrithione zinc improves its effectiveness against scalp conditions like dandruff.
November 2022 in “International journal of biology, pharmacy and allied sciences” In this study, the researchers formulated an herbal shampoo and found it exhibited excellent cleansing properties and foam stability, comparable to commercial shampoos, suggesting it as a safe and cost-effective alternative to marketed formulations.
3 citations
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January 1985 in “Drug development and industrial pharmacy” In this study, formulations of a typical lotion shampoo with ethanol or propylene glycol increased the in-vitro release rate of zinc pyrithione, an anti-dandruff agent.
January 1978 in “Yukagaku” This study found that using a zinc pyrithione-containing hair rinse significantly reduced dandruff and itching, with effects linked to the amount of zinc pyrithione residue on the hair.
1 citations
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November 2023 in “Journal of cosmetic dermatology” This study developed a novel antidandruff shampoo with ketoconazole-coated zinc oxide nanoparticles that showed enhanced antifungal activity against Malassezia furfur compared to standard ketoconazole treatments, suggesting it could be a more effective alternative for dandruff management.
February 2025 in “Biomimetics” This study developed a novel hair-straightening shampoo incorporating a polyphenol–inorganic sulfate redox agent, finding that it effectively straightens hair while enhancing strength and reducing damage due to its protective polyphenol coating.