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This study identified three genes with significantly higher expression in androgen-sensitive beard dermal papilla cells compared to androgen-insensitive scalp cells, suggesting potential novel signaling pathways in hair follicles.

In this study, Flii overexpression in mice enhanced fingertip regeneration and nail formation after both distal and proximal amputations, suggesting a role in digit and hair follicle regeneration possibly involving Wnt signaling.

Improve chin and perioral scars with surgery, resurfacing, and other therapies, tailored to each patient.

The researchers reported that finasteride treatment in male rats may lead to changes in antioxidant enzyme activity in their offspring's epididymis, potentially affecting sperm maturation.

This study found that the proteins GDNF, NTN, GFRα-1, GFRα-2, and c-Ret are differentially expressed during various stages of the human hair follicle cycle, with potential implications for hair biology.

This study suggests that fibromodulin may regulate transforming growth factor-β activity during scar formation, influencing the transition from fetal scarless repair to adult scar-forming repair in rats.

The researchers reported that during early embryogenesis and larval development in Silurana tropicalis, inhibiting steroidogenic enzymes cyp19 and srd5beta affects genes related to thyroid and reproductive systems.

In this study on Drosophila wings, researchers identified 435 genes with significant expression changes during wing hair morphogenesis, and found new phenotypes for 9 genes through functional validation.

This study found that chronic exposure to fadrozole or finasteride during frog development induced intersex individuals, which displayed different gene expression profiles depending on the chemical used.

Sfrp2 increases during hair follicle catagen phase and slows keratinocyte growth.

The tropical legume Sesbania rostrata can form nodules in waterlogged conditions using a different method that involves plant hormones and specific genes.

This study found significant differences in gene expression between newborn and adult skin, with infant skin notably increasing processes related to ECM organization, cell adhesion, and collagen fibril organization.

This study identified the N-(iodopropenyl) derivative 13 as a promising candidate for development as a radioiodinated androgen receptor ligand due to its binding affinity.

This study found that keratinocytes show increased expression of the TGF-β system and collagen type I with age, suggesting a heightened profibrotic response during skin differentiation associated with scarring.

This study found that ethanol extract of Tubtim Chumphae rice bran downregulates SRD5A gene expression, similarly to finasteride, suggesting potential use as an anti-hair loss product.

This study demonstrated that dermal papilla cells are molecularly distinct from fibroblasts and identified many novel molecules, including a new member of the CTGF protein family.

This study observed that 5% minoxidil topical foam alters gene expression and signaling pathways in the scalp, providing insights into its mechanism of action in men with androgenetic alopecia.

This study re-analyzed single-cell RNAseq data from human and mouse skin, confirming and refining insights into keratin gene regulation during keratinocyte differentiation in epithelial tissues.

This study found that glucose metabolism supports hair inductive gene expression and hair shaft elongation in dermal papilla cells, suggesting potential applications for in vitro hair follicle generation.

This study found that storing hair follicle grafts in chilled ATPv-supplemented saline was most effective for preserving trichogenic gene expression, compared to other storage solutions and temperatures.

This study found that several compounds from Yangxue Shengfa capsule may promote hair growth by enhancing cell proliferation in vitro, suggesting potential use in treating androgenetic alopecia.

Using a combination of specific cell cycle regulators is better for safely keeping hair root cells alive indefinitely compared to cancer-related methods.

This study found that administering testosterone to pregnant rats altered connexin 26 and connexin 43 expression in the uterus, which could disrupt embryo implantation and cause early pregnancy loss.

This study observed that storing hair follicle micrografts significantly decreased the expression of certain key genes in the dermal papilla, potentially affecting hair follicle cycling during preparation and storage.

This study found that activating TRPV4 in the skin of mice induced hair follicle regeneration by promoting anagen transition, suggesting potential treatment strategies for hair loss.

This study suggests a potential role for S100A7 and IL-17 in the pathogenesis of lichen planopilaris.

In this study, human dermal papilla cells exposed to wasabi leaf extract showed changes in cytokine-related gene expression, which the authors suggest could help clarify the biological effects of wasabi.

This study found that expressions of TLR-3, TLR-7, TLR-8, and TLR-9 were significantly higher in alopecia areata patients compared to healthy controls, indicating a potential role in disease autoimmunity.

This study observed that vimentin and transthyretin proteins were more highly expressed in black sheep skins compared to white, suggesting their involvement in coat color formation.

This study found that leukocytes and beard hair follicle cells have an endogenous circadian clock, with PER1 and PER3 expression possibly serving as biomarkers for assessing individual biological clock traits.