316 citations,
June 2017 in “Stem Cell Research & Therapy” Fat tissue-derived cells show promise for repairing body tissues, but more research and regulation are needed for safe use.
95 citations,
January 2004 in “Archives of Dermatological Research” Peripilar signs can help diagnose androgenetic alopecia and reveal its cause.
67 citations,
July 2016 in “Reviews in Endocrine and Metabolic Disorders” Stress can worsen skin conditions by affecting hormone levels and immune response.
65 citations,
June 2020 in “Stem Cell Research & Therapy” Certain immune system proteins are important for skin healing but can cause problems if there are too many of them.
65 citations,
March 2016 in “Lasers in Medical Science” Most low-level light therapy studies did not accurately report how light was measured, affecting treatment reliability.
61 citations,
January 2019 in “American Journal of Clinical Dermatology” The cause of Frontal Fibrosing Alopecia is unclear, diagnosis involves clinical evaluation and various treatments exist, but their effectiveness is uncertain.
58 citations,
December 2018 in “Nature Communications” Male pattern baldness is mostly inherited, involves many genes, and is linked to other traits like early puberty and strong bones.
50 citations,
July 2021 in “Nature Communications” The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.
49 citations,
March 2009 in “Archives of Gynecology and Obstetrics” Older age, higher BMI, and family history of diabetes increase the risk of gestational diabetes in pregnant women.
45 citations,
May 2018 in “Stem Cell Research & Therapy” Using patients' own fat-derived cells to treat alopecia areata significantly improved hair growth and was safe.
45 citations,
April 2018 in “Nature Reviews Urology” Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.
42 citations,
February 2021 in “Signal Transduction and Targeted Therapy” Hair follicle regeneration possible, more research needed.
42 citations,
November 2018 in “Archives of dermatological research” Apremilast was not effective in treating moderate-to-severe alopecia areata.
42 citations,
July 2017 in “Scientific Reports” Women with PCOS are more likely to have insulin resistance and obesity, especially those with the most severe type I PCOS.
40 citations,
December 2016 in “Journal of Ovarian Research” Rutin may help treat symptoms of polycystic ovary syndrome (PCOS) in rats.
39 citations,
March 2022 in “Nature Protocols” Scientists created hair-growing skin models from stem cells, which could help treat hair loss and skin diseases.
39 citations,
July 2021 in “Stem Cell Research & Therapy” Using fat stem cells and blood cell-rich plasma together improves healing in diabetic wounds by affecting cell signaling.
35 citations,
May 2021 in “Nature communications” The skin's basement membrane has specialized structures and molecules for different tissue interactions, important for hair growth and attachment.
33 citations,
April 2017 in “American journal of clinical dermatology” Early treatment of superficial fungal infections in immunocompromised patients is crucial.
32 citations,
January 2019 in “American Journal of Clinical Dermatology” Minoxidil helps treat eyebrow thinning, monilethrix, early hair loss, and shortens chemo-related hair loss.
29 citations,
January 2016 in “CNS drugs” Teriflunomide is effective and generally safe for treating relapsing-remitting multiple sclerosis.
28 citations,
March 2018 in “Archives of Dermatological Research” 27 citations,
April 2013 in “Reviews in endocrine and metabolic disorders” The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.
26 citations,
August 2019 in “Stem Cell Research & Therapy” PBX1 helps hair stem cells grow and change by turning on certain cell signals and preventing cell death, which may be useful for hair regrowth treatments.
26 citations,
May 2012 in “Cellular and Molecular Life Sciences” NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.
24 citations,
November 2023 in “Nature” The extracellular matrix affects where tumors can start in the body.
24 citations,
November 2017 in “Aesthetic Plastic Surgery” All types of Platelet-Rich Plasma (PRP) can treat hair loss, but homologous PRP works best due to its higher platelet count and growth factors from multiple donors.
23 citations,
November 2018 in “npj Regenerative Medicine” Healing of heart and skin wounds in animals are similar.
23 citations,
September 2016 in “Archives of Dermatological Research” Vitamin D levels do not affect the risk of developing alopecia areata.
23 citations,
January 2002 in “Journal of Cutaneous Medicine and Surgery” Finasteride helps hair growth by decreasing cell death in hair follicles.