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Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Different types of long-lasting stem cells are responsible for the growth and upkeep of the mammary gland.

Removing the ATR gene in adult mice causes rapid aging and stem cell loss.

Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.

Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.

Alopecia Areata is an autoimmune condition causing hair loss with no cure and treatments that often don't work well.

Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.

Targeting colon cancer stem cells might lead to better treatment results.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Half of people with Alopecia Areata may see hair regrowth within a year without treatment, but recovery is unpredictable.

Childhood obesity is rising globally due to various factors, and early prevention and healthy lifestyle changes are crucial.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.

Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.

Anticancer drugs are increasingly found in surface waters, and their long-term environmental effects are not well understood, requiring better testing methods.

The research found that PCOS has common genetic factors regardless of how it is diagnosed and is linked to metabolic and reproductive issues.

Hair regeneration needs dynamic cell behavior and mesenchyme presence for stem cell activation.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

The circadian clock affects skin stem cell behavior, impacting aging and cancer risk.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

Adult stem cells from rat whisker follicles can regenerate hair follicles and sebaceous glands.

Alopecia areata is an autoimmune condition causing hair loss, influenced by genetics, stress, and diet, and may be prevented by a high soy oil diet.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

PCOS is a complex disorder in women that can lead to various health risks and requires personalized treatment.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.