research Oncogenic Senescence: A Multi-Functional Perspective
Cellular senescence has both cancer-blocking and cancer-promoting effects, and targeting senescent cells may improve health and lifespan.
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research WNT10A, Dermatology and Dentistry
Mutations in the WNT10A gene can cause skin, hair, teeth, and other disorders, and may also affect other areas like kidney and cancer, with potential for targeted treatments.
research HSD3B1 Genotypes Conferring Adrenal-Restrictive and Adrenal-Permissive Phenotypes in Prostate Cancer and Beyond
Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.
research Ectodysplasin Research: Where to Next?
Future research on ectodysplasin should explore its role in diseases, stem cells, and evolution, and continue developing treatments for genetic disorders like hypohidrotic ectodermal dysplasia.
research What Does Acne Genetics Teach Us About Disease Pathogenesis?
Acne is significantly influenced by genetics, and understanding its genetic basis could lead to better, targeted treatments.
research Does a Male Polycystic Ovarian Syndrome Equivalent Exist?
Early onset baldness in men may indicate a condition similar to PCOS, linked to heart disease, diabetes, and prostate issues.
research Gene Expression of Type 2 17β Hydroxysteroid Dehydrogenase in Scalp Hairs of Hirsute Women
Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.
research MicroRNA in Skin Diseases
Certain microRNAs are linked to various skin diseases and could be used to diagnose and treat these conditions.
research Evidence for a Polygenic Contribution to Androgenetic Alopecia
Hair loss risk is influenced by multiple genes.
research Unveiling the Roots of Monogenic Genodermatoses: Genotrichoses as a Paradigm
New gene identification techniques have improved the understanding and classification of inherited hair disorders.
research Non-Canonical Dimerization of the Androgen Receptor and Other Nuclear Receptors: Implications for Human Disease
Mutations in certain receptors can cause diseases and offer new treatment options.
research Emerging Concepts About Prenatal Genesis, Aberrant Metabolism, and Treatment Paradigms in Polycystic Ovary Syndrome
PCOS may start before birth, involves metabolic issues, and can be treated with drugs like metformin and lifestyle changes.
research Thyroid Diseases and Skin Autoimmunity
Thyroid diseases may contribute to autoimmune skin diseases, and more research is needed on their relationship.
research Alopecia Areata: Pathogenesis, Genetic Factors, and Treatments Using Mouse Models
The document concludes that ongoing research using animal models is crucial for better understanding and treating Alopecia Areata.
research Group IID, IIE, IIF, and III Secreted Phospholipase A2s
Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.
research Higher Levels of Steroidogenic Acute Regulatory Protein and Type I 3β-Hydroxysteroid Dehydrogenase in the Scalp of Men with Androgenetic Alopecia
Men with baldness have higher levels of specific proteins, suggesting local hormone production may play a role in hair loss.
research Copy Number Variation Regions in Nellore Cattle: Evidence of Environmental Adaptation
Nellore cattle have genetic variations linked to their adaptation to tropical environments.
research Is Polycystic Ovary Syndrome a Sexual Conflict? A Review
The conclusion suggests that PCOS may persist due to genetic traits that, while harmful for female fertility, could have provided survival and reproductive benefits to males.
research Relationship of Early-Onset Baldness to Prostate Cancer in African-American Men
Early-onset baldness is linked to a higher risk of aggressive prostate cancer in African-American men, especially before age 60.
research Developmental Genetics of Color Pattern Establishment in Cats
Cat color patterns are determined early in development by gene expression and epidermal changes, with the Dickkopf 4 gene playing a crucial role.
research The Use of Mesenchymal Stromal Cells in the Treatment of Coronavirus Disease 2019
Mesenchymal stromal cells may help treat severe COVID-19, but more research is needed to confirm their effectiveness.
research Androgenetic Alopecia: Drug Safety and Therapeutic Strategies
Personalized treatment with inhibitors, minoxidil, and laser therapy helps hair loss.
research Differential Proteomics of Lesional vs. Non-Lesional Biopsies Revealed Non-Immune Mechanisms of Alopecia Areata
Non-immune factors play a significant role in alopecia areata.
research Polycystic Ovary Syndrome in Adolescents
The document concludes that diagnosing PCOS in teenagers is difficult and should focus on specific hormone levels and menstrual irregularities, while also considering treatment for symptoms and related health issues.
research Genetic Basis of Polycystic Ovary Syndrome
The document concludes that PCOS has a strong genetic component, but more research is needed to fully understand the specific genes involved.
research A Comparison of Transcriptomic Patterns Measured in the Skin of Chinese Fine and Coarse Wool Sheep Breeds
Fine wool sheep have more genes for wool quality, while coarse wool sheep have more for skin and muscle traits.
research PCOS: Update and Diagnostic Approach
The document concludes that more research is needed to fully understand the causes of PCOS.
research New Pharmaceutical Concepts for Sebaceous Gland Diseases: Implementing Today's Pre-Clinical Data into Tomorrow's Daily Clinical Practice
New treatments for skin conditions related to the sebaceous gland are being developed based on current research.
research Skin Diseases Due to Endocrine Alterations
Hormone imbalances can cause skin diseases, and understanding these links is important for diagnosis and treatment.
research Hormonal Regulation in Male Androgenetic Alopecia: Sex Hormones and Beyond - Evidence from Recent Genetic Studies
Hormones and genes affect hair growth and male baldness.