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This review outlines drug repurposing as an efficient, low-cost strategy to identify new uses for existing drugs, highlighting various computational and experimental approaches as well as publicly available databases to aid in personalized pharmacotherapy.

This review discusses the association between polycystic ovarian syndrome and hypertension, highlighting evidence of metabolic factors influencing this potential link and stressing the need for further research in this area.

This study found that activating TRPV4 in the skin of mice induced hair follicle regeneration by promoting anagen transition, suggesting potential treatment strategies for hair loss.

This study found that exposure to 50 Hz electromagnetic fields enhanced hair regrowth in mice by increasing stem cell proliferation and keratinocyte growth factor expression, suggesting potential benefits for hair loss treatment.

This study found that both finasteride and metformin effectively reduced androgen levels and insulin resistance parameters in women with PCOS, without clear evidence of one treatment being superior.

This study found that thyroid volume was increased in PCOS patients with insulin resistance, with potential influences from TSH and LH levels on these changes.

This study found that the FSHR Ser680Asn (rs6166) gene polymorphism is associated with an increased risk of PCOS in the examined population and could serve as a molecular biomarker for identifying risk.

This study found that greater root surface area due to root hairs contributed to better growth and zinc uptake of wild-type barley compared to its root-hairless mutant in zinc-deficient soil.

A woman's unique dementia was misdiagnosed, a genetic mutation increases Parkinson's risk with age, and finasteride may help with Tourette syndrome.

This review explores the role of the TMPRSS2 gene in facilitating SARS-CoV-2 infection and its potential as a therapeutic target in COVID-19 and other respiratory infections, highlighting challenges in developing selective inhibitors.

This study evaluated green tea extract-loaded spanlastic formulations and found that a vesicle builder to edge activator ratio of 8:2 produced optimal characteristics, including a particle size of 419.70 nm, an entrapment efficiency of 60.85%, and a drug loading of 11.07%.

This study developed finasteride-containing granules using a method that improved follicular targeting for androgenic alopecia and reported potential for easy industrial production.

This review examines host factors like ACE2 and TMPRSS2 in SARS-CoV-2 infection, exploring how genetic variants and advanced cellular analyses might clarify COVID-19's severity and heterogeneity; it reports no new results.

This study found that the protein OsUEV1B is essential for maintaining phosphate balance in rice, with Pi deficiency leading to its inhibition and causing overaccumulation of phosphate in mutants.

This study investigated single-cell changes in photoaged skin, revealing distinct cell clusters and increased activity in PD-L1 and PD-1 pathways in sun-exposed areas, enhancing understanding of UVA-induced skin damage and potential prevention targets for photoaging and UV-induced skin cancers.

This study found that men with early-onset androgenetic alopecia may experience less benefit from rosuvastatin treatment in terms of improving cardiometabolic risk factors compared to men with normal hair growth.

This study found that the medication dyclonine has a potent inhibitory effect on the TRPV3 channel, effectively rescuing cell death and alleviating pruritus symptoms in a mouse model with gain-of-function TRPV3 mutations, suggesting potential for treating skin inflammation.

This study found that Guasha therapy did not significantly alter nerve fiber morphology or the expression of CGRP and SP in rat skin, with parameters generally returning to normal within five days.

This chapter discusses the current developments in Traditional Chinese Medicine for treating PCOS but reports no new clinical results, emphasizing the need for further research in this area.

This article reviews the identification and assessment of cutaneous drug reactions, emphasizing the importance of early recognition and the need for accurate diagnosis to prevent serious complications; it reports no new clinical results.

In this study, researchers developed a new murine model for transplanting vibrissae that mimics human hair transplantation, achieving successful hair growth in immune-deficient nude mice.

This study found that human chymase overexpression in transgenic mice may contribute to increased mortality from LPS treatment compared to wild-type mice.

This study found that METTL1 is upregulated in papillary thyroid cancer tissues and promotes cancer cell proliferation and metastasis through its tRNA methyltransferase activity.

This systematic review and meta-analysis found 30 genetic loci associated with skin ageing phenotypes, noting shared biological pathways in aspects like pigmentation and wrinkling; researchers suggest further studies targeting the same SNP across populations could clarify these associations.

This study observed that disrupting the Pnkp gene in adult mice resulted in a premature aging-like phenotype, suggesting PNKP's vital role in maintaining normal growth and survival of certain progenitor cell populations.

In this study, researchers developed a method called the Stiffness-Angle Law and found that hair treated with caffeine-infused shampoo showed a 13.2% increase in stiffness, as measured by their novel evaluation technique.

This case study describes a child with severe cicatricial alopecia that began at birth and progressed rapidly, making treatment results disappointing.

This study found that the repressive histone mark H2AK119ub links inhibitory FGF signals with the quiescent state in hair follicle stem cells, revealing a signaling-epigenetic axis crucial for maintaining stem cell quiescence and tissue homeostasis.

This study explored the optimization of phytochemicals from Alstonia boonei to develop potential 5-alpha reductase inhibitors for Benign Prostatic Hyperplasia, finding promising analogs with enhanced binding affinity and stability compared to Finasteride, warranting further experimental validation.

This study investigated the genetic basis of coat color variation in cattle using skin transcriptome and whole-genome analyses, identifying the ASIP gene as a significant determinant that is differentially expressed and under strong positive selection in black and brown cattle breeds.