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Nanoparticles can enter the skin, potentially causing toxicity, especially in damaged skin.

Nanocarrier-loaded gels improve drug delivery for cancer, skin conditions, and hair loss.

Skin grafts are effective for chronic leg ulcers, especially autologous split-thickness grafts for venous ulcers, but more data is needed for diabetic ulcers.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

Certain drugs that block specific enzymes can help treat prostate diseases.

Toxic epidermal necrolysis is a severe skin reaction often linked to drugs, requiring careful medication use and supportive care.

Nanoparticulate systems improve drug delivery by controlling release, protecting drugs, changing absorption and distribution, and concentrating drugs in targeted areas.

Sorafenib helps some advanced cancers alone or with other treatments, but not all, and research continues to improve its use.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.

The S100A4 protein is more common in psoriatic skin and could be a target for treating psoriasis.

Dutasteride effectively treats enlarged prostate, reduces prostate cancer risk, and promotes hair regrowth with few side effects.

*Acorus calamus* has many medicinal benefits but needs more safety research.

Nano-sized plant-based chemicals could improve cervical cancer treatment by being more effective and causing fewer side effects than current methods.

Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.

Organotypic culture systems can grow skin tissues that mimic real skin functions and are useful for skin disease and hair growth research, but they don't fully replicate skin complexity.

Vitamin C helps adipose-derived stem cells grow and may support hair growth.

Skin aging is largely due to differences in stiffness and elasticity between skin layers, leading to wrinkles.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

SCF and c-Kit decrease in AGA hair follicles, possibly affecting hair pigmentation and growth.

Scalp cooling can help prevent chemotherapy-induced hair loss with a 50-90% success rate and is safe for patients.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

The skin is a complex barrier that protects the body, regulates temperature, and helps with immune responses.

New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.

Mice are useful for researching human hair loss and testing treatments, despite some differences between species.

Cell aging can be both good and bad for tissue repair.

Patient-derived melanocytes can potentially treat vitiligo by restoring skin pigmentation.

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

Breast cancer patients taking CDK4/6 inhibitors are more likely to experience fatigue, hair loss, and mouth sores.

Men with baldness at the front and top of their head at age 45 may have a higher risk of aggressive prostate cancer.