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Minoxidil and finasteride treat hair loss; more research needed for other options.

Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.

Prostate cancer prevention includes diet changes, supplements, and medications, with more answers expected soon.

Topical drugs and near-infrared light therapy show potential for treating alopecia.

Advanced human skin models improve drug development and could replace animal testing.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Alisertib was found to be an effective and tolerable treatment for children with recurrent brain tumors.

Nanoparticles can enter the skin, potentially causing toxicity, especially in damaged skin.

Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.

Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.

Multiphoton microscopy is a promising tool for detailed skin imaging and could improve patient care if its challenges are addressed.

Nanocarrier-loaded gels improve drug delivery for cancer, skin conditions, and hair loss.

Skin grafts are effective for chronic leg ulcers, especially autologous split-thickness grafts for venous ulcers, but more data is needed for diabetic ulcers.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

Hydrogels could lead to better treatments for wound healing without scars.

Certain drugs that block specific enzymes can help treat prostate diseases.

Toxic epidermal necrolysis is a severe skin reaction often linked to drugs, requiring careful medication use and supportive care.

Nanoparticulate systems improve drug delivery by controlling release, protecting drugs, changing absorption and distribution, and concentrating drugs in targeted areas.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Sorafenib helps some advanced cancers alone or with other treatments, but not all, and research continues to improve its use.

Disrupting Acvr1b in mice causes severe hair loss and thicker skin.

*Acorus calamus* has many medicinal benefits but needs more safety research.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

Dutasteride effectively treats enlarged prostate, reduces prostate cancer risk, and promotes hair regrowth with few side effects.

Nano-sized plant-based chemicals could improve cervical cancer treatment by being more effective and causing fewer side effects than current methods.

Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.

The conclusion is that fat grafting is safe and effective but carries risks that need careful management.

Organotypic culture systems can grow skin tissues that mimic real skin functions and are useful for skin disease and hair growth research, but they don't fully replicate skin complexity.

Vitamin C helps adipose-derived stem cells grow and may support hair growth.