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Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.

Hibiscus plant extracts may have health benefits like lowering blood pressure and protecting the heart.

Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.

Skin fat helps with body temperature control and has other active roles in health.

Researchers found a specific immune receptor in patients that causes severe skin reactions to a drug.

The treatment combining docetaxel, cisplatin, and 5-FU is feasible and effective for advanced head and neck cancer.

Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Alisertib was found to be an effective and tolerable treatment for children with recurrent brain tumors.

Nanoparticles can enter the skin, potentially causing toxicity, especially in damaged skin.

Skin grafts are effective for chronic leg ulcers, especially autologous split-thickness grafts for venous ulcers, but more data is needed for diabetic ulcers.

Toxic epidermal necrolysis is a severe skin reaction often linked to drugs, requiring careful medication use and supportive care.

Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.

The skin is a complex barrier that protects the body, regulates temperature, and helps with immune responses.

Patient-derived melanocytes can potentially treat vitiligo by restoring skin pigmentation.

Breast cancer patients taking CDK4/6 inhibitors are more likely to experience fatigue, hair loss, and mouth sores.

Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.

Toxic Epidermal Necrolysis is a rare, serious skin condition that can affect anyone, is more common in women, and may be linked to genetics, with a 20% mortality rate mainly due to sepsis.

Certain herbal compounds, especially from bitter melon, can inhibit cancer growth and promote hair growth by blocking PAK1.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Older people's sweat glands are less effective at helping skin wounds heal due to weaker cell connections.

GPR39 is linked to certain cells in the sebaceous gland and helps with skin healing.

GFP transgenic mice help study cell origins in skin grafts.

Low doses of BPA can increase prostate growth and change hormone levels in adult rats.

ECM-inspired wound dressings can help heal chronic wounds by controlling macrophage activity.

Stem cell therapies show promise for treating various diseases but face challenges in clinical use and require better monitoring techniques.

Saw palmetto supplements may reduce prostate cancer cell growth without being toxic.