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PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.

The PW91 method is best for calculating the basic physical and chemical properties of Finasteride, a drug used for prostate issues and hair loss.

Fluridil safely promotes hair growth in men with androgenetic alopecia.

Researchers developed new compounds that target the androgen receptor effectively with fewer side effects.

Metformin may help treat neuroendocrine tumors.

Forsythiaside A helps reduce brain damage from lack of blood flow by activating certain protective pathways.

Taking Dutasteride with Ketoconazole can increase Dutasteride's effects and side effects.

Long-term use of difluprednate eye drops in dogs can lead to hair loss and hormone imbalance.

Decursin shows promise for treating cancer, neuroprotection, inflammation, and hair loss.

Cationic and nonionic surfactants provide better color intensity and resistance for semi-permanent hair dye than anionic surfactants.

L-cystine, D-pantothenat, and miliacin together significantly boost keratinocyte growth and metabolism.

Liver enzyme helps minoxidil work better for blood vessel relaxation.

Reconstructed skin models are useful for studying how skin processes certain chemicals.

Wild African goats have genetic adaptations for surviving harsh desert conditions.

Cytochrome P-450 enzymes in the skin help break down various substances and could be targeted to treat skin conditions.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

Hair is a complex organ, and understanding its detailed structure and growth phases is crucial for analyzing substances within it.

Hair analysis is crucial for diagnosing, managing, and monitoring addiction.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Tiny pollution particles called PM2.5 can harm skin cells by causing stress, damage to cell parts, and cell death.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Tributyltin exposure causes sex changes, sterilization, and decline in the snail Ocinebrina aciculata, risking its extinction.

Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

The circadian clock is crucial for tissue renewal and regeneration, affecting stem cell functions and having implications for health and disease.

Different types of skin pores should be identified correctly and evaluated with suitable methods for reliable results.

The document concludes that understanding sulfation biology is crucial for creating treatments due to its importance in biological functions and disease.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.