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Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

The document reviews various hair and nail disorders, their causes, and treatments, emphasizing the need for proper diagnosis and the link between nail changes and systemic diseases.

A new genetic change causing early stop in the androgen receptor gene was found in a patient with androgen insensitivity syndrome.

Tyrosine kinases are important in skin autoimmune diseases and could be targets for new treatments.

The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.

Fibroblast growth factors are crucial for hair follicle development and regeneration.

Reduced AR gene methylation may cause early pubic hair growth in girls.

A specific RNA, circNlgn, contributes to heart damage and scarring caused by the cancer drug doxorubicin.

The conclusion is that androgen receptor gene polymorphism might be a marker for polycystic ovary syndrome, but more research is needed.

Androgen receptors in the mouse brain may explain cognitive and mood changes in prostate cancer treatment.

A young man with an eating disorder had a life-threatening adrenal crisis due to an autoimmune condition, highlighting the need for better education on managing hormone treatments.

Men and women get COVID-19 at similar rates, but men tend to get sicker and have a higher risk of dying, while women usually have stronger immune responses and vaccine reactions.

Gene therapy has potential as a future treatment for Hutchinson-Gilford progeria syndrome.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Men with early hair loss may have a higher risk of enlarged prostate and possibly prostate cancer due to shared hormonal factors.

The Asiatic lion has very low genetic diversity and unique genetic traits, highlighting the need for its conservation.

Sex hormones like estrogen and testosterone may affect COVID-19 severity differently in men and women, potentially influencing prevention and treatment strategies.

Researchers found genetic mutations causing hypohidrotic ectodermal dysplasia in 88% of studied patients and identified new mutations and genetic variations affecting the disease.

Transplant success has improved with better immunosuppressive drugs and donor matching.

A genetic test can identify people at risk of male pattern baldness early, allowing for quicker treatment.

Finasteride in male rats causes liver and metabolic issues in their offspring.

A boy with Sjogren-Larsson syndrome has skin and muscle symptoms due to a specific enzyme deficiency.

The lotion and shampoo effectively treated scalp seborrheic dermatitis.

Air pollution (PM10) increases skin inflammation and aging by reducing collagen and may trigger a repair response in skin cells.

DHT affects hair follicle cells by changing microRNA levels, leading to less cell growth and more cell death.

An 11-year-old girl with a rare skin disorder also had cornea issues and dry eye, needing careful management.

Treg cell-based therapies might help treat hair loss from alopecia areata, but more research is needed to confirm safety and effectiveness.

The length of the CAG repeat in the androgen receptor gene affects the risk and progression of prostate cancer, BPH, infertility, and undermasculinized genitalia.

Finasteride may effectively treat hair loss in Klinefelter Syndrome patients.