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Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Certain mutations in a hair growth-related gene cause a type of genetic hair loss.

K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.

Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.

Researchers found a new gene area linked to male-pattern baldness, which, along with another gene, significantly increases the risk of hair loss in men.

A genetic region near the PAX1 gene is linked to a higher risk of scoliosis in females.

The EDAR gene greatly affects hair thickness in Asian populations.

A new gene, JMJD1C, may affect testosterone levels in men.

The triterpenoids from Ganoderma lucidum can block testosterone effects and may help treat enlarged prostate.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

Topical immunotherapy, especially with DPCP, is effective for treating severe alopecia areata.

A gene variation is linked to hair thickness in Asians.

Gonadal dysgenesis, like Turner's and Klinefelter's syndromes, negatively affects bone health, but hormone treatments can help.

CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.

Mice lacking fibromodulin have disrupted healing patterns, leading to abnormal skin repair and scarring.

Mice that can regenerate tissue have cells that pause in the cell cycle, which is important for healing, similar to axolotls.

Researchers created a mouse model of a type of rickets that does not cause hair loss.

Genetic variants linked to ten skin diseases were found, showing both immune and non-immune factors play a role.

Researchers found a safe and effective way to pick genetically modified skin cells with high growth potential using CD24.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

Finasteride may negatively affect male fertility.

Stopping the pill and giving birth both caused hair loss.

New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.

A Japanese patient with IFAP syndrome had a severe MBTPS2 gene mutation but showed milder symptoms than previously observed cases.

Two women with very high androgen levels had only slight skin issues, one due to a non-classical adrenal disorder and the other due to an adrenal tumor.

The skin protects the body, regulates temperature, senses touch, and makes vitamin D.