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The document explains hair and nail biology, common hair loss conditions and treatments, oral and genital skin diseases, and the risks and treatments associated with squamous cell carcinoma.

The document reviews various hair and nail disorders, their causes, and treatments, emphasizing the need for proper diagnosis and the link between nail changes and systemic diseases.

Histone demethylases play a key role in the development of many diseases and may be targets for treatment.

Finding functions for unknown GPCRs is hard but key for making new drugs.

Blocking the Mitochondrial Pyruvate Carrier causes stress in hair follicles, which can be reduced by an ISR inhibitor.

Cynoglossum amabile has medicinal potential but poses safety concerns due to liver toxicity.

MSC-protein helps regenerate gum tissue and bone.

Different light affects cell functions and can help treat skin conditions.

Hormonal imbalances are a key cause of missed menstrual periods in women.

Patients with acne vulgaris have lower serum irisin levels.

The research identified and described a gene important for hormone conversion in endangered catfish, which varies in activity during different reproductive stages and after hormone treatment.

Keedari thailam is effective for treating alopecia areata and has multiple health benefits.

Innovative methods are reducing animal testing and improving biomedical research.

Garudan Kizhangu Ennai may effectively treat alopecia areata but needs more research to confirm its safety and effectiveness.

Ayurveda's descriptions of genetic disorders align with modern genetic understanding.

PRP helps heal and repair tissues in medicine but needs more research for better use.

Seasonal changes affect gene activity linked to hair growth in Angora goats.

A group has developed therapies that show promise for treating cancer and various other conditions.

Seasonal changes affect hair growth genes in Angora goats, possibly influencing mohair quality.

Certain changes in the SHBG gene may increase the risk of PCOS in Iraqi women.

A new genetic change in the DSC3 gene is linked to a rare condition causing hair loss and skin blisters in a child.

Targeting NETs may help reduce fibrosis in Crohn's disease.

No single biomarker is reliable enough for diagnosing and assessing SLE.

The document concludes that the development of certain tumors is influenced by genetic background and that a specific gene modification can lead to tumor regression and reduced growth.

Wild African goats have genetic adaptations for surviving harsh desert conditions.

Gene therapy in mice increased lifespan and improved health without causing cancer.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

Selective breeding can enhance immunity in dairy cattle.

The HoxC gene cluster and its enhancers are essential for developing hair and nails in mammals.

A mother and daughter have a rare genetic hair loss disorder with no effective treatment.