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New cancer treatments show promise in reducing tumor growth and improving skin regeneration in mice.

This chapter reviews classification and techniques of surgical therapies for treating stable, recalcitrant vitiligo, highlighting their role alongside non-surgical methods for small, specific cases.

A protein called FGF9 helps regenerate hair follicles in mice after skin damage, and increasing FGF9 could potentially help human hair growth.

This study provided the first proteome dataset for alopecia areata, revealing novel pathways in the disease mechanisms that may lead to new therapeutic targets.

This study identified a novel mechanism by which dsRNA-induced TLR3 activation and retinoic acid pathways contribute to new hair follicle formation after deep wounds in mice and suggested a similar potential in humans.

This study suggests that hair follicle dermal stem/progenitor cells play a key role in both hair regeneration and skin wound healing, with potential implications for preventing hair follicle miniaturization linked to aging or alopecia.

This study found that wounding in skin induces significant fibroblast heterogeneity and recruits myeloid cells, which contribute to adipocyte regeneration in mice.

This review discusses the unique capacity of fetal skin to heal wounds without scarring and notes that while many factors have been identified, the complete mechanism of fetal wound healing remains unclear.

This study found that α-MSH administration before skin wounding in adult mice reduced inflammation and scar area, suggesting a potential pathway to more regenerative healing.

This article explores how adult mammals can regenerate hair follicles after wounding and suggests that manipulating cell signals during healing might enhance this process, but provides no new experimental results.

This study found that vimentin is essential for proper wound healing and cell growth by influencing EMT signaling and mTOR activity in mice.

This study found that inhibiting DPP4 during a critical period post-wounding increases hair follicle regeneration and Wnt signaling in large skin wounds.

This study found that MK6a-deficient mice showed delayed reepithelialization after superficial wounding but not after full-thickness skin wounds, suggesting MK6a plays a role in activating follicular keratinocytes post-wounding.

In this study, full-thickness wounding on Lanyu pigs led to scar formation and disrupted cell markers, while partial-thickness wounding allowed limited regeneration of rete ridges and papillary dermis.

This study demonstrates that bacteria contribute to hair follicle neogenesis after skin wounding through IL-1R1 signaling in keratinocytes.

This study shows that macrophage-induced TNF signaling can activate hair follicle stem cells and promote new hair follicle formation after wounding by regulating AKT/β-catenin pathways.

This article reviews a new method to accurately estimate proliferative and migratory epithelial cell numbers post-wounding but reports no experimental findings; the authors suggest its relevance to skin stem-cell biology research.

This study found that manipulating both gene expression and matrix stiffness in mice can alter hair regeneration after skin wounding, highlighting key factors in regenerative biology.

This study found that Shh from neurons signals to Gli1-expressing cells in the hair follicle, cultivating a niche where these bulge cells can potentially transform into epidermal stem cells in wound healing.

In this study, the researchers found that vitamin D and calcium signaling in keratinocytes are essential for normal skin regeneration after wounding, with deficiencies significantly delaying wound closure and re-epithelialization in mice.

In this study, basal cell carcinoma developed in Ptch-deficient mice only after chemical treatment, not skin wounding, suggesting a second unknown event is necessary for tumor formation.

This study found that Caspase-1, traditionally viewed as an inflammasome component, is secreted upon wounding and plays a novel role by triggering hair follicle stem cell migration into the epidermis, offering insights into epithelial hyperplasia mechanisms in inflammatory skin conditions.

This article discusses the follicular unit excision process in hair restoration, focusing on the balance between donor site wounding and graft retrieval, and provides no new clinical data.

This study found that anagen skin in PVG rats showed significantly smaller wound diameters compared to telogen skin at 7 and 8 days after wounding, suggesting the importance of hair follicle dermal components in wound healing.

In this study, researchers using single nuclei RNA-sequencing found that fibroblasts in deeper layers of mouse skin expressed higher levels of pro-inflammatory genes post-wounding compared to other cells, highlighting their significant role in early inflammation and tissue repair processes.

In this study, researchers explored the molecular and cellular traits of avian reticulate scales, finding that they lack localized stem cell niches for regeneration, unlike other scale types, leading to repair but not regeneration after wounding.

In this study, researchers found that in adult mice, new hair follicles with pigmentation can regenerate from the epidermis after skin wounding, aided by melanocyte stem cells moving from nearby existing hair follicles.

This study found that collagen VI is crucial for peripheral nerve function and regeneration, and its absence promotes abnormal hair regrowth after skin wounding in mice, revealing potential therapeutic targets for nerve injuries and hair loss.

This study found that, while hair follicle bulge stem cells are important for hair follicle survival and epidermal regeneration after wounding, the epidermis maintains itself independently of these cells under normal conditions.

This study found that Lgr5 and Lgr6 stem cells both activated wound-healing genes, but only Lgr5 stem cells changed their identity to contribute to new skin formation during wound repair.