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In this study, wound closure tension following strip surgery for hair restoration varied by strip width, highlighting the importance of minimizing tension to achieve better scarring outcomes.

This study investigated the role of the glycoprotein Thy-1 in hypertrophic scar formation using a murine model, finding that Thy-1 knockdown reduced scar size and encouraged functional regeneration by influencing the p38MAPK signaling pathway under high-tension conditions.

This study found that filamin A plays a crucial role in fibroblasts' ability to sense and respond to mechanical stimuli, significantly affecting wound closure and fibroblast-mediated processes in mice.

This review discusses the mechanisms of wound healing and excessive scarring, highlighting the importance of understanding these processes for developing new therapies to prevent fibrotic scarring in large skin wounds.

This review highlights emerging evidence that biophysical and metabolic cues, such as oxygen levels and tissue mechanics, significantly influence skin stem cell behavior, which is crucial for developing advanced wound healing therapies beyond traditional infection and inflammation control.

This study suggests that mechanical tension significantly impacts lymphocyte function, and that a complete lymphocyte population is essential for effective wound healing and reducing inflammation.

This study suggests that peri-incisional triamcinolone acetonide may subtly benefit wound edge apposition in low-tension scalp regions during hair restoration surgery, but shows no statistically significant overall effect.

This narrative review discusses the advantages of bidirectional barbed sutures in wound closure, such as faster placement and no need for knots, but reports no new clinical results.

This study reported that a new surgical technique resulted in minimal scars visible to the naked eye in most cases, suggesting a significant improvement over conventional closure techniques.

This review discusses the role of mechanical forces in skin homeostasis and disease development, including their impact on conditions like keloids, androgenetic alopecia, and acral melanoma, and reports no clinical results; the authors propose modifying these forces as a potential therapeutic strategy.

This study presented a case series of erosive pustular dermatosis on the scalps of elderly patients, noting unusual presentation with hypergranulation tissue and unique dermoscopic vascular patterns, diverging from typical manifestations.

This study found that using deep plane fixation during scalp surgeries significantly reduced closure tension and allowed for increased tissue excision compared to standard techniques without fixation.

This study found that deep plane fixation in scalp surgeries allowed for tension-reduced wound closures and increased tissue excision compared to techniques without deep plane fixation.

This study found that BMP2 increased PTEN expression and induced autophagy, promoting hair follicle stem cell differentiation in both in vitro models and a mouse wound model.

This article proposes two new categories of cicatricial alopecia—“unstable” and “stable”—and suggests surgical excision as preferred over hair transplantation, especially for unstable cases.

This article reviews various reconstructive surgery techniques for scalp wounds and emphasizes factors affecting aesthetic outcomes, but it presents no new clinical findings.

This study found that Fraser's Dolphin, a tight-skinned mammal, can regenerate complex skin architecture with minimal scarring after large full-thickness wounds, even in high-tension environments, offering insights into regenerative healing mechanisms typically obscured by fibrotic responses.

This study found that large excisional wounds in mice can regenerate new hair follicles and fat, whereas similar wounds in rats across seven strains failed to do so, highlighting interspecies differences in regenerative capacity.

This case series reports successful treatment of refractory folliculitis decalvans using surgical excision with second-intention healing and guarded high-tension suturing, resulting in long-term remission without recurrence over a 10–24 month follow-up period.

This review discusses recent advances in scarless wound healing research, focusing on the roles of mechanobiology and immunology, and reports no new clinical results; the authors highlight the potential of next-generation human skin equivalents in understanding these mechanisms.

This narrative review from the authors discusses mechanical scalp stimulation as a potential treatment for androgenetic alopecia, suggesting it has a biologically plausible mechanism but immature clinical evidence; marketing of these devices currently outpaces their supporting data, indicating a need for better-controlled trials.

This narrative review suggests that while mechanical scalp stimulation has a plausible mechanism for aiding androgenetic alopecia, its clinical evidence is insufficient, and the marketing of stimulation devices currently outpaces their efficacy data.

This study found that culturing fibroblasts on stiffer substrates mimicking fibrotic wounds led to an aligned EDA fibronectin matrix with thinner fibers and decreased YAP activity, suggesting disrupted signaling that might be restored to promote regenerative wound repair.

This review examines the mechanisms behind pathological scarring like hypertrophic scars and keloids, highlights the limitations of current treatments, and suggests that biomaterial-enabled delivery of anti-fibrotic statins, such as atorvastatin, may offer a promising therapeutic avenue for managing these scars.

This article proposes several potential approaches for scar prevention and therapy, including anti-transforming growth factor-β strategies and tissue-engineered skin, but reports no new clinical results.

This paper contains no findings, serving instead as contact information for a dermatologist with no financial conflicts of interest disclosed.

In this study, researchers found that patients who previously had hair restoration surgery by a different surgeon were more likely to experience postoperative hyperesthesia.

This case report highlights the successful use of the Bardach modification of the curved tripod flap for repairing cicatricial pressure alopecia, offering a natural appearance and effective tension distribution in scalp reconstruction.

This case report describes a dual transposition flap technique for closing large scalp defects post-Mohs surgery, achieving minimal alopecia and scar visibility, though it is based on a single patient.

This chapter examines common and less common complications associated with the strip method of hair transplantation and discusses management strategies, but it does not report new clinical results.