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    Glossary Wound Re-epithelialization

    process where new skin cells cover a wound

    Wound re-epithelialization is the process by which new skin cells (keratinocytes) migrate across a wound to restore the integrity of the skin barrier. This critical phase of wound healing involves the proliferation and movement of these cells to cover the wound surface, ultimately leading to the formation of new tissue and the closure of the wound.

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    1. Dendritic epidermal T cells secreting exosomes promote the proliferation of epidermal stem cells to enhance wound re-epithelialization Stem Cell Research & Therapy · 2022 · 24 citations
    2. DNA Damage-Inducible Transcript 4 Is an Innate Surveillant of Hair Follicular Stress in Vitamin D Receptor Knockout Mice and a Regulator of Wound Re-Epithelialization International journal of molecular sciences · 2016 · 22 citations
    3. Thyrotropin-Releasing Hormone (TRH) Promotes Wound Re-Epithelialisation in Frog and Human Skin PLOS ONE · 2013 · 46 citations
    4. Inhibition of the CoREST Repressor Complex Promotes Wound Re-Epithelialization through the Regulation of Keratinocyte Migration Journal of Investigative Dermatology · 2023 · 8 citations
    5. M-CSF-stimulated myeloid cells can convert into epithelial cells to participate in re-epithelialization and hair follicle regeneration during dermal wound healing PLOS ONE · 2022
    6. Novel Biodegradable Polymeric Microparticles Facilitate Scarless Wound Healing by Promoting Re-epithelialization and Inhibiting Fibrosis Frontiers in Immunology · 2018 · 37 citations
    7. ALKBH5-mediated m6A demethylation fuels cutaneous wound re-epithelialization by enhancing PELI2 mRNA stability Inflammation and Regeneration · 2023 · 8 citations
    8. M-CSF-stimulated myeloid cells can convert into epithelial cells to participate in re-epithelialization and hair follicle regeneration during skin wound healing 2021
    9. Moist exposed burn ointment accelerates diabetes-related wound healing by promoting re-epithelialization Frontiers in Medicine · 2023 · 24 citations
    10. Platelet-rich plasma accelerates skin wound healing by promoting re-epithelialization Burns & Trauma · 2020 · 169 citations
    11. Nanoclay gels promote re-epithelialization and improve the quality of skin wound healing in a diabetic mouse model npj Regenerative Medicine · 2026
    12. The Yin and Yang of Integrin Function in Re-Epithelialization During Wound Healing Advances in Wound Care · 2013 · 8 citations
    13. Negatively Charged Carbon Dot‐Linked Glycyrrhizic Acid Hydrogel Promoted Hemostasis, Immunoregulation and Re‐Epithelialization of Wound Closure Small · 2026
    14. 658 The epigenetic control of re-epithelialization during adult skin wound healing Journal of Investigative Dermatology · 2024
    15. 1α,25-Dihydroxyvitamin D3 accelerates skin wound re-epithelialization by promoting epidermal stem cell proliferation and differentiation through PI3K activation: an in vitro and in vivo study Brazilian Journal of Medical and Biological Research · 2025 · 2 citations
    16. Cultured Keratinocyte Sheets Enhanced Spontaneous Re-Epithelialization in a Dermal Explant Model of Partial-Thickness Wound Healing Journal of Investigative Dermatology · 1990 · 42 citations
    17. Combined Deletion of the Vitamin D Receptor and Calcium-Sensing Receptor Delays Wound Re-epithelialization Endocrinology · 2017 · 28 citations
    18. Insight into Reepithelialization: How Do Mesenchymal Stem Cells Perform? Stem Cells International · 2015 · 40 citations
    19. Reepithelialization of a Full-Thickness Burn from Stem Cells of Hair Follicles Micrografted into a Tissue-Engineered Dermal Template (Integra) Plastic and Reconstructive Surgery · 2004 · 87 citations
    20. Activin Controls Skin Morphogenesis and Wound Repair Predominantly via Stromal Cells and in a Concentration-Dependent Manner via Keratinocytes ˜The œAmerican journal of pathology · 2005 · 81 citations
    21. Reflections on how wound healing-promoting effects of the hair follicle can be translated into clinical practice Experimental Dermatology · 2014 · 43 citations
    22. RGDSP-functionalized peptide hydrogel stimulates growth factor secretion via integrin αv/PI3K/AKT axis for improved wound healing by human amniotic mesenchymal stem cells Frontiers in Bioengineering and Biotechnology · 2024 · 6 citations
    23. Immune Cells in Cutaneous Wound Healing: A Review of Functional Data from Animal Models International Journal of Molecular Sciences · 2022 · 5 citations
    24. Dermal papilla cell-derived exosomes promote hair follicle regeneration during wound healing by activating Wnt/β‐catenin signaling pathway Research Square (Research Square) · 2024
    25. Proangiogenic and Collagen-Promoting Effects of a 70% Ethanol Extract of Grateloupia angusta in Cutaneous Wound Models International Journal of Molecular Sciences · 2026
    26. An Extended Epidermal Response Heals Cutaneous Wounds in the Absence of a Hair Follicle Stem Cell Contribution 2007 · 170 citations
    27. Epithelial–Mesenchymal Plasticity and Endothelial–Mesenchymal Transition in Cutaneous Wound Healing Cold Spring Harbor Perspectives in Biology · 2022 · 31 citations
    28. Epithelial stem cells and implications for wound repair Seminars in Cell & Developmental Biology · 2012 · 156 citations
    29. Epithelial‐to‐mesenchymal transition in cutaneous wound healing: Where we are and where we are heading Developmental Dynamics · 2017 · 141 citations
    30. 17β-Estradiol Inhibits Wound Healing in Male Mice via Estrogen Receptor-α American Journal Of Pathology · 2010 · 38 citations