August 2025 in “Plastic and Aesthetic Research” This review discusses recent advancements in microneedle technology for hair loss treatment, highlighting their ability to enhance drug delivery and improve hair follicle survival in transplantation, while also exploring their potential integration with tissue engineering to address regeneration challenges.
This review discusses the potential of using Arabidopsis thaliana to express fusion protein TDP1-KGF-2, aiming to enhance the transdermal delivery of KGF-2 for hair growth applications, despite current challenges with production costs and efficacy.
August 2024 in “International Journal of Nursing Studies Advances” In this research, the authors concluded that the long-term success of hair transplantation for androgenetic alopecia is significantly influenced by how well patients manage their recovery period post-surgery.
In this narrative review, the authors explored various rehabilitative techniques, including injections and physical therapies, that may enhance aesthetics and psychosocial wellbeing in patients with disabilities, emphasizing a multidisciplinary approach to improve both functional and cosmetic outcomes.
March 2024 in “Biomedicines” This review examines the mechanisms, recent findings, and strategies to enhance mesenchymal stem cells' therapeutic effects in skin wound healing, but reports no new research results.
This review concluded that the efficacy of cosmeceutical hair serums for addressing hair loss lies in their use of bioactive peptides and plant compounds, like flavonoids and sterols, that target eight key contributing factors identified in hair loss conditions.
May 2013 in “Springer eBooks” Skin problems in the elderly are unique and may indicate other diseases, involving changes in skin, hair, nails, and increased cancer risk.
July 2003 in “Journal of Cutaneous Medicine and Surgery” Skin problems are common in Bangladesh due to arsenic, prompt treatment of diabetic foot ulcers is crucial, maternal transmission causes most neonatal herpes, treatments for pediatric vasculitis are effective, the chickenpox vaccine works, more frequent UVB therapy helps psoriasis, certain jobs increase hand dermatitis risk, monoclonal antibodies treat psoriasis well, lifestyle affects psoriasis, alefacept improves psoriasis, imiquimod cream partially clears basal cell carcinoma, and iron may not help chronic hair loss.
2 citations
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November 2025 in “Cells” This review presents evidence supporting the potential of adipose-derived stem cell secretome as a promising cell-free therapy for skin repair, emphasizing its application in wound healing, alopecia, skin rejuvenation, and inflammatory skin diseases.
December 2023 in “Medicine” This study observed that platelet-rich gel for scalp defect reconstruction was more cost-effective and less painful but resulted in poorer hair growth compared to the external tissue expansion technique.
822 citations
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January 2021 in “Genome biology” This study presents a new method called scMC that effectively distinguishes biological from technical variation in single-cell genomics datasets, demonstrating its ability to accurately align and detect biological signals across various experiments.
517 citations
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February 2010 in “Materials” This review discusses the history and development of keratin biomaterials for biomedical uses, highlighting their biological activity and biocompatibility, and provides no new research findings.
154 citations
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November 2017 in “Development” This review discusses the roles of fibroblast growth factors in tissue regeneration and repair across various organisms and tissues, but reports no new experimental findings, underscoring the need for further research.
92 citations
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April 1999 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that keratin 9 expression in nonpalmoplantar keratinocytes can be induced by signals from palmoplantar fibroblasts, potentially enabling the use of nonpalmoplantar epidermis to treat palmoplantar wounds.
54 citations
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January 2023 in “Signal Transduction and Targeted Therapy” This review examines integrins as pharmacological targets, discussing current integrin-based therapies and emphasizing the need to understand integrin mechanisms for successful drug development, without reporting new clinical results.
44 citations
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October 2019 in “International Journal of Molecular Sciences” This article reviews various studies and suggests that melatonin, produced both naturally in the skin and applied topically, may offer significant protection against environmental damage, making it a promising candidate for skincare therapies.
41 citations
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September 2021 in “Materials” This review discusses the role of biomaterials and colloidal drug delivery systems in promoting tissue regeneration within regenerative medicine, but it reports no new clinical results.
41 citations
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August 2015 in “The FASEB Journal” The researchers reported that topical application of small-molecule Wnt inhibitors significantly reduced fibrosis and promoted regenerative wound healing in mice.
29 citations
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December 2019 in “Transfusion and Apheresis Science” This review discusses platelet-derived bio-products for tissue regeneration in various medical fields and reports no new clinical results; it highlights the need for a standardized classification to compare clinical outcomes effectively.
26 citations
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January 2024 in “Gels” This review highlights advancements in nanoemulgel platforms for topical and transdermal drug delivery, noting their improved safety and efficacy over conventional treatments in in vitro and in vivo studies, specifically for conditions like skin diseases and inflammatory issues.
26 citations
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July 2021 in “Frontiers in Cell and Developmental Biology” This review discusses mesenchymal stromal cell-conditioned medium for various skin conditions and found improvements in wound healing, hair restoration, and more, but emphasizes the need for further research to validate these findings.
22 citations
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February 2023 in “Heliyon” This study reports that a heparin-based sericin hydrogel encapsulating basic fibroblast growth factor significantly accelerated wound healing in mice by enhancing vascularization, re-epithelialization, and collagen deposition.
22 citations
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June 2001 in “International Journal of Cosmetic Science” This review discusses the role of iron from cosmetic sources in skin nutrition and reports no clinical results, highlighting its significance for skin, hair, and nail health.
13 citations
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May 2021 in “FASEB bioAdvances” This review discusses plant-based alternatives to retinoids for dermal antiaging and hair health, highlighting roles for cytokinins and phytoestrogens and reports no new results.
9 citations
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June 2019 in “Plastic & Reconstructive Surgery Global Open” This study reviewed the outcomes of a limited incision lateral brow lift technique, reporting that the procedure safely resolved lateral brow hooding with a low revision rate in 150 patients, and observed no permanent nerve injuries.
7 citations
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December 2024 in “Antibiotics” This review discusses the potential of cathelicidins in treating skin conditions but highlights significant challenges, including unclear clinical efficacy, safety concerns, and bacterial resistance, that must be addressed for successful medical application.
5 citations
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October 2022 in “Cosmetics” This article reviews in-vitro and cell-free methods for assessing the efficacy of herbal ingredients in cosmetic formulations for skin health and hair growth, but it reports no new clinical results.
5 citations
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May 2021 in “EMBO journal” This review discusses the role of polarity signaling in coordinating tissue mechanics, micro-environmental functions, and cell fate decisions, but it reports no new results, highlighting the need for further study in mammalian models.
4 citations
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January 2022 in “Transfusion Medicine and Hemotherapy” This review discusses the varied applications of platelet-rich plasma in plastic surgery and reports mixed evidence on its efficacy, indicating a need for more standardized, controlled trials.
3 citations
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December 2023 in “Cell proliferation” This review suggests that the umbilical cord-derived mesenchymal stem cell secretome presents a promising approach for skin regeneration and wound healing due to its multiple therapeutic properties, highlighting its potential over traditional treatments for conditions like chronic wounds and alopecia.