January 2026 in “AppliedMath” This study explored a mechanism for making Turing pattern formations more predictable and robust by isolating pattern modes to prevent their sensitivity to initial conditions, which can lead to different outcomes from minor initial changes.
September 2025 in “Acta Biomaterialia” In this study, researchers developed injectable micropore-forming hydrogels that enhance tissue adhesion strength and promote wound healing by allowing better cell infiltration and inducing hair follicle regeneration in skin incision wound models.
January 2025 in “Medicina” This study reviews emerging techniques in acute burn wound therapy, noting innovations such as advanced imaging for better wound assessment and new closure strategies aimed at improving healing, graft survival, and scarring outcomes, while emphasizing the need for further research to validate these methods.
January 2025 in “International Journal of Endocrinology” This study found that the hydroalcoholic extract of the Dorema aucheri plant, especially at a 5% concentration, enhanced diabetic wound healing in male rats, improving re-epithelialization, collagen deposition, and neovascularization more effectively than other tested concentrations.
November 2022 in “IntechOpen eBooks” This review discusses nanoparticle-based wound-healing materials, detailing their benefits, limitations, and recent advancements, and emphasizes the need for further understanding to enhance therapeutic outcomes.
16 citations
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April 2021 in “Biomedicines” This study found that ferulic acid promotes wound healing by inhibiting β-catenin in keratinocytes and activating Nrf2 to reduce inflammation at the wound edge.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study introduces the N-K Healing Series, an alternative geometric approach to medicine, claimed to restore tissue fully and eliminate pain without the traditional drawbacks, allegedly achieving results beyond mainstream medical treatments in simulated injury scenarios.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study presents the N‑K Healing Series, a geometric approach to medicine that claims to restore tissue geometry, eliminate pain, and regenerate burns more effectively than traditional treatments, with simulations demonstrating significant improvements in healing outcomes and reduced scarring.
January 2025 in “Burns & Trauma” This review paper highlights that titanium dioxide nanoparticles (TiO2 NPs), due to their biological properties like antioxidant, anti-inflammatory, and antimicrobial effects, show promise in accelerating wound healing and enhancing tissue regeneration when used in scaffolds and dressings.
36 citations
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January 2017 in “Stem Cells International” This study found that Wnt7a-containing conditioned medium from UC-MSCs can accelerate wound healing and promote hair follicle regeneration by enhancing specific cellular functions in the wound microenvironment.
216 citations
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February 2022 in “Nanomaterials” This review discusses the potential of electrospun gelatin-based nanofiber dressings for wound healing and skin regeneration, detailing their properties, enhanced functionalities through crosslinking and bioactive components, and their application in treating challenging wound types like burns and diabetic wounds.
25 citations
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January 2024 in “International Journal of Nanomedicine” The hydrogel is safe, reduces oxidation, and helps heal wounds effectively.
12 citations
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May 2024 in “International Journal of Nanomedicine” This review discusses the potential of stem cell-derived extracellular vesicles for improving diabetic wound healing and highlights their mechanisms, limitations, and challenges, but provides no new clinical findings.
January 2025 in “Pharmaceuticals” This review discusses the potential of peptide-based hydrogels as biomaterials for treating chronic wounds and reports no new clinical findings.
30 citations
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September 2024 in “Pharmaceuticals” This research highlights the potential of using bioactive silk-based nanofiber dressings to improve the healing of diabetic wounds, suggesting that further studies are needed to refine these formulations and confirm their effectiveness in larger clinical trials.
527 citations
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December 2011 in “Proceedings of the National Academy of Sciences” This study found that dextran-based hydrogels promoted significant neovascularization and skin regeneration in mouse models of third-degree burns, without the need for additional growth factors or cells.
169 citations
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October 2020 in “Pharmaceutics” This review discusses recent advancements in formulating electrospun nanofibers as wound dressings, emphasizing their advantages in incorporating bioagents for improved healing, but reports no new clinical results.
83 citations
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May 2021 in “Biomolecules” This study found that an injectable composite hydrogel containing cerium bioactive glass improved wound healing in diabetic rats by promoting angiogenesis and offering antibacterial properties, suggesting its potential for enhancing diabetic foot wound repair.
7 citations
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June 2025 in “Nano Energy” This study reports that triboelectro-responsive DNA hydrogels, enhanced with conductive polymers and triboelectric stimulation, effectively accelerate wound healing and exhibit strong anti-bacterial and anti-inflammatory properties, achieving 99.8% closure of bacterium-infected diabetic wounds in 14 days.
5 citations
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December 2024 in “Bioengineering” In this study, conditioned medium from genetically engineered mesenchymal stem cells significantly improved wound healing, re-epithelialization, hair follicle formation, and angiogenesis in diabetic mice, suggesting a promising new approach for diabetic ulcer care.
January 2023 in “International Journal of Molecular Sciences” This study found that a double-crosslinked hydrogel using GelMA and sulfhydrylated chitosan showed promising results in healing full-thickness skin wounds in rats by accelerating tissue repair and promoting collagen and blood vessel formation.
40 citations
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January 2022 in “Frontiers in Chemistry” This study found that a microneedle array patch using a blend of kangfuxin, chitosan, and fucoidan significantly accelerated wound healing in rats by enhancing epithelial thickness and collagen deposition.
July 2023 in “Bioengineering & translational medicine” This study explored a cell-free therapy with mesenchymal stem cell paracrine proteins and PEG hydrogels for deep burn treatment and found that the combination significantly enhanced wound healing, reduced scar formation, and promoted skin appendage regeneration in a rabbit model.
78 citations
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February 2024 in “ACS Omega” This study developed a bilayer material combining poly(vinyl alcohol) and bacterial cellulose with a gelatin-poly(vinyl alcohol) hydrogel, showing strong potential as a wound dressing due to its good antibacterial properties, cell viability, and sustained drug release.
12 citations
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September 2023 in “Polymers” This study reported that a newly developed hydrogel composed of recombinant type I collagen and chitosan, incorporating a metal–polyphenol structure, demonstrated strong mechanical and healing properties, effectively promoting wound healing in a full-thickness skin defect model.
April 2025 in “Journal of Skin and Stem Cell” This review discusses the potential of polydeoxyribonucleotide (PDRN) for various dermatological treatments and highlights its significant effects on wound healing, anti-aging, acne scars, and hair loss, but emphasizes the need for further clinical studies.
84 citations
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August 2013 in “Journal of Cellular Biochemistry” This study found that stem cells from the human umbilical cord's Wharton's jelly may significantly enhance healing in excisional and diabetic wounds compared to controls.
7 citations
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February 2024 in “ACS Applied Materials & Interfaces” This study found that PEGylated Ag₂S-ZnS@TGA-AA heteronanostructures, activated by light exposure, showed synergistic antibacterial effects against multidrug-resistant bacteria, significantly accelerating the healing of MRSA-infected wounds in comparison to untreated wounds.
This study suggests that a specific subpopulation of umbilical cord-derived mesenchymal stem cells, CMD, may enhance wound healing and tissue quality in chronic skin ulcers, with promising results in both murine and equine models.