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The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.

The study found that sweat glands contain different types of stem cells that help with healing and maintaining healthy skin.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

Planarian regeneration begins with a specific gene activation caused by injury, essential for healing and tissue regrowth.

Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.

Some medicinal plants can help heal wounds and may lead to new treatments.

Overexpressing follistatin in mice delays wound healing and reduces scar size.

Different types of stem cells in hair follicles play unique roles in wound healing and hair growth, with some stem cells not originating from existing hair follicles but from non-hair follicle cells. WNT signaling and the Lhx2 factor are key in creating new hair follicles.

Bioprinting could improve wound healing but needs more development to match real skin.

Fetal wound healing changes with development, affecting inflammation and collagen, which may influence scarring.

Lowering testosterone speeds up wound healing in male mice.

UV radiation can help sterilize wounds and promote healing but requires careful use to avoid damaging cells.

Wharton’s Jelly stem cells from the umbilical cord improve skin healing and hair growth without scarring.

Blocking β-catenin in skin cells improves hair growth during wound healing.

Activin helps skin growth and healing mainly through stromal cells and affects keratinocytes based on its amount.

Created material boosts hair growth and kills bacteria for wound healing.

The conclusion is that hair growth can be improved by activating hair cycles, changing the surrounding environment, healing wounds to create new hair follicles, and using stem cell technology.

Fetal skin cells from a cell bank heal wounds faster and with less scarring than adult cells.

Vigilon, a new wound dressing, promotes faster and better healing with less pain.

Certain immune system proteins are important for skin healing but can cause problems if there are too many of them.

PHBV nanofiber matrices help wounds heal faster when used with hair follicle cells.

Microneedles are effective for painless drug delivery and promoting wound healing and tissue regeneration.

A special dressing called FEA-PCEI can speed up wound healing, reduce scars, and help grow new hair follicles, but only at the right dosage.

The silk fibroin-based hydrogel shows promise for treating melanoma and healing infected wounds by killing tumor cells and bacteria, and supporting skin recovery.

Testosterone may slow down wound healing and increase inflammation.

Tcf3 helps cells move and heal wounds by controlling lipocalin 2.

Wound dressing absorbs fluid, regenerates hair follicles, and heals skin burns.

The nanohybrid system significantly improved wound healing and showed strong antibacterial activity.

The new skin patch with human matrix and antibiotic improves wound healing.

A new hydrogel with stem cells from human umbilical cords improves skin wound healing and reduces inflammation.