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Certain proteins, caspases-1 and -11, are important in the early development of skin inflammation in mice.

Alopecia significantly lowers women's quality of life, with psychological and social challenges, highlighting the importance of early treatment and support.

Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Metformin and rosiglitazone improve blood vessel function in women with PCOS, with metformin also reducing insulin resistance and testosterone levels.

Drugs targeting the JAK/STAT pathway can improve atopic dermatitis but vary in effectiveness for vitiligo and alopecia areata, with generally mild safety concerns.

Some drugs may reduce prostatitis symptoms short-term with few side effects.

Stem cells help repair tissue mainly by releasing beneficial substances, not by replacing damaged cells.

The study found that certain microRNAs are higher in the cells and lower in the fluid of women with a specific type of polycystic ovary syndrome, and one microRNA could potentially help diagnose the condition.

The research found that anovulatory young women have higher androgen and hormone levels than those who ovulate, suggesting immature hormonal regulation rather than a specific condition.

Mutations in the hairless gene in mice affect its expression and lead to a range of developmental issues in multiple tissues.

Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.

The conclusion is that acne, alopecia, and hyperhidrosis are common skin issues with various treatments available, and accurate diagnosis is key for effective management.

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.

Finasteride for hair loss may cause persistent sexual symptoms, depression, anxiety, and lower quality of life.

Spironolactone improved blood vessel function and cholesterol levels in non-obese women with PCOS.

Different treatments for alopecia areata have varying success rates and side effects; intralesional steroids are most effective.

A 3-month stay in space causes skin thinning, disrupts hair growth, and changes muscle-related genes in mice.

Exosomes can improve skin health and offer new treatments for skin repair and rejuvenation.

A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.

Understanding the genetics of rare inherited ichthyosis syndromes is key for better treatments and genetic counseling.

The LRRK2-G2019S mutation in Parkinson's disease has a lifetime penetrance of 25-35%, and finasteride may help reduce symptoms in adult male Tourette syndrome patients.

People with hair loss conditions experience more anxiety, depression, and a lower quality of life than those without these conditions.

Finasteride reduces Tourette syndrome symptoms, but results may be limited due to potential biases.

Alopecia areata seriously lowers quality of life, especially affecting self-image, mental health, and social life.

Finasteride caused long-term sexual and non-sexual side effects in young men with hair loss.

The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.