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This study suggests that β-catenin plays an important role in wool follicle development in transgenic sheep by enhancing the expression of keratin protein genes.

This study found that straight crimp mutant wool differs from crimpy wool in the layout of cortical cells and the relative proportions of keratin and keratin-associated proteins.

This study found that intradermal spermidine injections stimulated cell proliferation and increased fibre length growth rate in wool follicles of Merino lambs, without significantly affecting fibre diameter.

This study found that ethionine significantly inhibited wool growth in sheep, with L- and D-isomers being equally effective, but did not cause hair loss in sucking mice or rats.

Using minoxidil and tretinoin on the skin, along with oral vitamin D, improved hair thickness and density in two girls with woolly hair.

This study used TMT-based quantitative proteomics to analyze the development of secondary hair follicles in fetal sheep, revealing increased follicle density and key proteins involved, such as COL1A1 and THBS4, indicating their potential role in wool quality traits.

This review discusses the genetic origins of autosomal recessive woolly hair with hypotrichosis and reports no clinical results; it highlights the link to homozygous variants in the K25 keratin gene.

This case report describes a 5-year-old girl with trichorrhexis nodosa and highlights the presence of isolated curly hairs on her scalp despite hair loss over four months.

This study reported three related cases of woolly hair syndrome transmitted as a dominant autosomal trait, characterized by fine, frizzy hair and general hair thinning.

This study found that Magra sheep with high-luster wool exhibited significantly higher expression of keratin genes, suggesting that increased keratin protein levels may be crucial for wool luster.

This study found that keratinocytes derived from the germinative epithelium of ovine hair follicles have extensive in vitro growth potential, challenging the idea that these cells are solely transit-amplifying.

In this study, researchers found that wool growth regulation is likely achieved through endocrine growth factors, with various growth factors inhibiting fibre growth in vitro.

No clear conclusion available.

This case report describes a new family with autosomal recessive hypotrichosis simplex with woolly hair, suggesting the disorder may be underreported due to misdiagnosis.

This review discusses insights into the role of lipase H in controlling hair form and texture, emphasizing genetic mutations linked to autosomal recessive woolly hair/hypotrichosis, and reports no new experimental results.

In this study, researchers found two non-synonymous SNPs in the TERT gene associated with mean wool staple strength in sheep, suggesting TERT as a potential candidate gene for improving wool traits.

This study found that MEG3-miRNAs are key regulators of the age-dependent crimped wool trait in Tan sheep, likely influencing primary follicle development and degeneration through immune-inflammatory pathways.

In this study, researchers found that oar-miR-377 regulates secondary hair follicle development in sheep by downregulating the SLC24A2 gene, and a specific SNP in oar-miR-377 is significantly associated with wool fiber diameter variation in Chinese Merino sheep.

In this study, topical application of keratin extract from wool promoted hair growth in mice by reducing the time for initiation and completion of growth phases and improving hair quality.

This study found that variation in the ovine KRTAP27-1 gene may influence wool growth, with certain genotypes associated with higher mean staple length and greasy fleece weight in sheep.

This study introduces a modular fiber model to investigate how changes in microstructural properties of wool affect its critical buckling load, highlighting potential uses and areas needing further research in wool fiber biophysics.

In this study, researchers identified and analyzed 8,753 circular RNAs in Aohan fine wool sheep, suggesting that certain circRNAs may play a crucial role in regulating wool follicle growth.

In this study, a porous keratin hydrogel derived from wool hair demonstrated strong mechanical properties and supported the growth of various animal cells, indicating potential as a scaffold in tissue engineering.

In this study of Swedish sheep herds, nutritional deficiencies and telogen effluvium, possibly due to cold stress after shearing, were suggested as primary causes of wool loss.

This study found that adding sheep wool-waste or human hair-waste to soil increased yields and secondary metabolites in various crops and supported up to five harvests without additional fertilizers, though it decreased mycorrhizae colonization.

This paper examines factors affecting the stretching setting treatment of human hair and wool, concluding that the intended outcomes can be achieved using their customized testing equipment and technology.

This study observed increased metallothionein expression in regenerating liver and hyperplastic mouse skin, suggesting a potential role in cellular proliferation and differentiation.

This case series describes eight instances of autosomal recessive woolly hair in an Indian population over the past 12 years, detailing their clinical presentation, hair traits, and treatment response.

This study explored a mother and daughter with loose anagen hair syndrome linked to wooly hair, identifying an intronic variant in the KRT71 gene that affects hair keratin splicing, thus broadening the spectrum of KRT71-related disorders.

This study reviewed the medical literature on generalized woolly hair and reported that while there are no effective treatments, some narratives suggest that topical Minoxidil may help with hypotrichosis associated with the condition.